DNA Flashcards

1
Q

What is in a nucleotide

A

A sugar base and phosphate group

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2
Q

Key features of a polynucleotide

A

Nucleotides are joine together by phosphdiester bonds
The chain has polarity 5’ to 3’
The chain has distinct ends 5’ ( phosphate end) and 3’ (sugar end)

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3
Q

Polynucleotide secondary strucutre

A

Nucleic acids can form duplex structure
Strands are complementary
Strands are a itparrellel
Can have DNA-DNA, RNA-RNA strands and DNA-RNA strands

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4
Q

What is in a nucleoside

A

A base and sugar

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5
Q

describe how DNA is packaged

A
double helix 
nucleosomes 
solenoids 
solenoid loops 
chromosomes
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6
Q

Define genome

A

the entire DNA sequence

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7
Q

give four key features of DNA replication

A

needs separation fo DNA strands
occurs in a step wise reaction
reaction driven by pyrophosphate hydrolysis
chain gortwh is directional from 5 to 3’

semi conservative

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8
Q

what are the consequences of meiosis

A

maintain constant chromosome number from generation to generation

creates genetic diversity from random assortment and crossing over

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9
Q

what is the role of meiosis

A

production of four non identical cells with half the chromosome content of partent cell

diploid cell is reduced to haploid cell

special cell division for germ line cells

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10
Q

describe a mistake in meiosis

A

the chromosomes do no segregate properly

can cause miscarriages
infertility
mental retardation

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