DNA Flashcards
What is in a nucleotide
A sugar base and phosphate group
Key features of a polynucleotide
Nucleotides are joine together by phosphdiester bonds
The chain has polarity 5’ to 3’
The chain has distinct ends 5’ ( phosphate end) and 3’ (sugar end)
Polynucleotide secondary strucutre
Nucleic acids can form duplex structure
Strands are complementary
Strands are a itparrellel
Can have DNA-DNA, RNA-RNA strands and DNA-RNA strands
What is in a nucleoside
A base and sugar
describe how DNA is packaged
double helix nucleosomes solenoids solenoid loops chromosomes
Define genome
the entire DNA sequence
give four key features of DNA replication
needs separation fo DNA strands
occurs in a step wise reaction
reaction driven by pyrophosphate hydrolysis
chain gortwh is directional from 5 to 3’
semi conservative
what are the consequences of meiosis
maintain constant chromosome number from generation to generation
creates genetic diversity from random assortment and crossing over
what is the role of meiosis
production of four non identical cells with half the chromosome content of partent cell
diploid cell is reduced to haploid cell
special cell division for germ line cells
describe a mistake in meiosis
the chromosomes do no segregate properly
can cause miscarriages
infertility
mental retardation