Inhaled corticosteroids Flashcards
MoA
Reduces inflammation in bronchi
BD dosing
Beclometasone
Budesonide
Fluticasone
Mometasone (BD/OD)
OD dosing
Ciclesonide
Rx by brand
- CFC-free inhalers are not interchangeable.
- QVAR is twice as potent as Clenil modulite.
- QVAR is more potent that CFC-containing inhalers.
Use
Must take regularly for 3-4 weeks for prevention/to see improvement
Fostair
- Extra fine particles
- More potent that traditional CFC-Free inhalers (QVAR + Clenil)
Refrigerate
Side effects
Hoarse voice
Sore throat
Oral candidiasis
Oral candidiasis
Prevention = rinse mouth + brush teeth after using OR use a spacer.
Treatment = Daktarin gel (NOT with warfarin!!)
Paradoxical bronchospasm
Stop and give alternative
Mild bronchospasm = use SABA before or use dry powder instead of pMDI
Smoking
Current + previous history of smoking = reduced effectiveness (patient may need higher dose)
Steroid card
Give in high dose ICS that is greater than the max licensed dose.
Spacer
Use in:
- High dose ICS
- Patients under 15