Inhalation Therapy Flashcards
For Stroke; Used w/ Mucolytics, for expectoration
1
Q
What is the DEFINITION of INHALATION Therapy?
A
- Use of any drug / solution administered by the nasal / oral respiratory route
2
Q
What is the MECHANISM of Inhalation Therapy?
A
1) If the Particle is LESS than < 1 micrometre = Can reach till the Alveoli
2) If the Particle is 0.5 - 5 micrometre = Can reach Beyond the 10th Gen of Bronchi
3) If the Particle is MORE than > 5 micrometre = Can reach Oropharynx
3
Q
What are the FACTORS affecting Particle DEPOSITION?
A
PHYSIOLOGICAL
- Lung Morphology
- Inspiratory Flow Rate
- Tidal Volume
- Breath Holding
PHARMACEUTICAL
- Aerosol viscosity
- Size / Shape / Density
- Physical stability
4
Q
What are the 5 TYPES of AEROSOL GENERATORS?
A
- Metered Dose Inhaler (MDI)
- Dry Powder Inhaler (DPI)
- Spacer
- Rotahaler
- Nebulisers = Used to covert solution into aerosol particles
5
Q
What are TYPES of Nebulisers?
A
- Jet Nebulisers
- Ultrasonic Nebulisers
6
Q
What DRUGS are used for Nebulisation?
A
- Distilled / Mineral Water, or Saline
- Mucolytics = Acetylcysteine
- Beta-2 Agonists = Salbutamol / Salmeterol
- Antimuscarinics
- Steroids
- Antibiotics / Antifungals
7
Q
What are the ADVANTAGES / DISADVANTAGES of Inhalation Therapy?
A
ADVANTAGES
- LESS Systemic Toxicity
- Rapid Onset of action
- Delivery to Target of action
- HIGHER CONC allowed in the Lung
DISADVANTAGES
- Time / Effort consuming
- Complex Delivery Devices are required
8
Q
What are the INDICATIONS of Inhalation Therapy?
A
- Asthma
- Bronchitis
- COPD
- Emphysema
- Bronchiectasis
- Stroke
