Inflammatory Heart Disorders Flashcards
ineffective endocarditis
disease of the endocardial layer of the heart, including the heart valves
which valves do ineffective carditis mostly affect
aortic and mitral
classification by cause for ineffective endocarditis
IV drug use (IV drug abuse), fungal
classification by involvement for ineffective endocarditis
prosthetic valve endocarditis (PVE)
causative organisms for ineffective endocarditis
bacterial, virus, fungi
which bacteria are the most common for ineffective endocarditis
s. aureus; streptococcus viridians; coagulase negative staphylococci
risk factors for IE
categories of high, moderate, and low risk of developing ineffective endocarditis
principal risk factors for ineffective endocarditis
prosthetic valves; hemodialysis; IV drug abuse
etiology and physiology for ineffective endocarditis
there are 3 stages: bacteremia, adhesion, and vegetation
vegetation
fibrin, leukocytes, platelets, and microbes; stick to the valve or endocardium; parts break off and enter circulation
left sided vegetation moves to
brain, kidneys, spleen
right sided vegetation moves to
lungs
clinical manifestations of IE
nonspecific, fever, chills, weakness, malaise, fatigue, anorexia
subacute forms of IE
arthralgias, myalgias, back pain, abdominal discomfort, weight loss, headache, clubbing of fingers
vascular manifestations
splinter hemorrhages in nail beds; petechiae; osler’s nodes on fingertips/toes; janeway’s leisons on pads of the fingers and toes; roth’s spots; new or worsening systolic murmur in most patients; heart failure
manifestations secondary to septic embolism
CNS, extremities, spleen, and kidneys