INFLAMMATORY CYTOKINES Flashcards
1
Q
Which are the main inflammatory cytokines and what are their effects?
A
IL-1, TNF and IL-6 (induced by IL-1 and TNF).
Local effects when they are at low levels: vascular effects.
Systemic effects when they are at high levels: fever, acute phase proteins and hematopoiesis.
Septic shock (SIRS) when they are at too high levels: hypovolemic shock, DIC and multi organ failure.
