CITOTOXICITY DEFECTS Flashcards
1
Q
What are the main cytotoxic cells?
A
NK cells
Cytotoxic T lymphocytes
2
Q
How does it function the cytotoxicity process?
A
Cell-cell interaction
Cell conjugate formation
Docking
Exocytosis
Cytotoxic granules
3
Q
What are the main mechanisms of target cell recognition of NK cells?
A
ADCC
Natural cytotoxicity
4
Q
Main cytotoxicity defects
A
HLH
XLP