Inflammatory Bowel diseases Flashcards

1
Q

Inflammatory bowel disease includes

A

ulcerative colitis and crohn’s

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2
Q

differences of ulcerative colitis and crohn’s onset

A

C-gradual, UC- sudden or gradual

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3
Q

differences of ulcerative colitis and crohn’s distribution

A

C-mouth to anus, skip areas, UC- distal to proximal, no skip

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4
Q

differences of ulcerative colitis and crohn’s depth of lesion

A

C- trasmural, UC- mucosal

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5
Q

differences of ulcerative colitis and crohn’s symptoms

A

C- diarrhea/pain, UC- bloody, pus, diarrhea, tenesmus

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6
Q

differences of ulcerative colitis and crohn’s complications

A

C-fistulas, toxic megacolon, colon CA, UC: toxic megacolon and colon cancer

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7
Q

Ulcerative cholitis

A

chronic recurrent disease, starts at rectum and moves proximally, contained within colon, toxic megacolon and malignancy are more likely in UC than C, smoking is protective

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8
Q

Symptoms of UC

A

inflammatory diarrhea, tenesmus, pain in LLQ (rare), weight loss, malaise, fever

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9
Q

Diagnosis of UC

A

CBC: anemia, ESR: increased, Albumin: decreased, Xray will show colonic dilatation, diagnostic is colonoscopy (avoid in severe) or sigmoidoscopy

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10
Q

Treatment of UC

A

topical or oral aminosalicylates, corticosteroids, immunomodulators, surgery can be curative

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11
Q

Crohn’s disease

A

cause is unknown, genetic predispostion, involves: s/l colon, mouth, esophagus, stomach, but mostly terminal ileum and r colon, not usually rectum, has skip areas

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12
Q

Symptoms of Crohn’s

A

abdominal cramps, chronic diarrhea,

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13
Q

Diagnosis of crohn’s

A

anemia, increased ESR, electrolyte imbalances colonoscopy, biopsy, granuloma common

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14
Q

Treatment of Crohn’s

A

acute: oral corticosteroids, Maintenance: mesalamine, MTX, smoking cessation, B12, folate, Vit D, surgery is not curative

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15
Q

Toxic megacolon

A

Emergency, extreme dilatation and immobility of colon, Hirschsprung’s disease, ulcerative colitis, Crohn’s. and infectious causes

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16
Q

Symptoms of toxic megacolon

A

fever, prostration, severe cramps, abd distention

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17
Q

Diagnosis of Toxic megacolon

A

rigid abd, rebound tenderness, xray shows colon dilatation

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18
Q

Treatment of Toxic megacolon

A

Decompression of the colon, fluid and electrolyte balances

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19
Q

Ischemic bowel disease

A

Acute or chronic, >50 yo, intestinal infarction is more common in the small bowel than large, shock is common

20
Q

Acute mesenteric ischemia

A

emergency, high mortality, arterial embolus/thrombus, venous thrombosis, sudden onset of severe abd pain

21
Q

Chronic mesenteric ischemia

A

blood supply is present but insufficient, abd angina and pain 10-30 min after eating, relieved by squatting or lying down

22
Q

Diagnosis of ischemic bowel

A

Ct to rule out other abd causes, diagnostic is colonoscopy

23
Q

Treatment of ischemic bowel disease

A

surgery to revascularize intestine, hydration

24
Q

Intussusception

A

invagination of proximal segment of bowel into portion distal to it, most common in children

25
Symptoms of intussusception
children: colick, stoll will contain blood and mucus (jelly stool), abd pain, sausage like mass adults: crampy, no blood, abd pain, mass is rare
26
Diagnosing intussusception
children:barium or air filled most diagnostic, adult: barium enema should not be used, Xray is not specific, CT best, usually found in surgery
27
Treatment of intussusception
hospitalized, air or barium enema may be curative, surgery or resection
28
Common small bowel obstruction
adhesions, hernias, neoplasm, inflammatory bowel disease, volvulus
29
Common large bowel obstruction
neoplasm, strictures, hernias, volvulus, intussusception, fecal impaction
30
Symptoms of small bowel obstruction
abd pain, distention, vomiting of partially digested food, opstipation, high pitched bowel sounds, later bowel is silent
31
Symptoms of large bowel obstruction
distention and pain, may be febrile, tachy, shock
32
Diagnosing bowel obstruction
CMP: decreased electrolytes, upright CT shows air fluid levels
33
Treatment of bowel obstruction
NPO, NG, IV fluids, monitoring, surgery likely with large intestine
34
Volvulus
emergency, twisting of bowel on self, sigmoid or cecal area, ischemia can lead to gnagrene, peritonitis and sepsis
35
Symptoms of bowel volvulus
Cramping abd pain and distention, tachy, nausea, vomiting, obstipation, fever, severe pain
36
Diagnosing Volvulus
xray shows colonic distension
37
Treatment of volvulus
immediate decompression to avoid ischemia, endoscopic depression with surgeon stand by
38
Diverticular disease
Diverticulosis are pocket formations, diferticulitis is infection, >60% >60 have, 20% are asymptomatic, 20% have acute
39
Symptoms of diverticular disease
sudden onset in LLQ, fever, nausea, diarrhea, blood
40
Diagnosing diverticular disease
occult blood, elevated WBC, X ray to rule out free air, CT if pt does not respond to therapy, barium enema avoided
41
Treatment diverticular disease
antibiotic treatment (Cipro, flagyl), pt education on diet, and meds
42
Treatment of severe diverticulitis
hospitalization, IV antibiotics, NPO, NG tube, surgical management
43
Appendicitis
obstruction of appendix leads to inflammation and infection, commonest cause of fecalith and ER surgery, 10-30 yo, 10% of pop, 20% of pt develop peritonitis and perforation
44
Symptoms of appendicitis
progressive, intermittent periumbical pain, than RLQ localization, nausea and anorexia, vomiting/diarrhea, low grade temp
45
Diagnosis of appendicitis
increased WBC, blood and leukocytes in UA, abdominal CT w/ contrast