Inflammatory Bowel Disease Flashcards

1
Q

types of IBD

A

crohn’s dz (refractory enteritis) and ulcerative colitis

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2
Q

chron’s dz

A

genetic predisposition

may involved small and large bowels, mouth, esophagus, stomach, terminal ileum and right colon involved, skips the rectum

skip areas characteristic

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3
Q

complications of chron’s dz

A

fistuals, abscesses, aphthous ulcers, renal stones, predisposition to colon cancer

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4
Q

common sx of chrons

A

abdominal cramps, D in pt younger than 40

low-grade fever, polyarthralgia, anemia, and fatigue

blod

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5
Q

chrons dx

A

colonoscopy
bx-show entire bowel wall involvments

*granulomas common

** contrast and endoscopic procerdures should be avoid in pts w. fulminant (explosive sudden) dz - worry about toxic megacolon/perforation

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6
Q

more blood tests for chrons

A

ESR, anemia, nutritional/electrolye imbalance during exacerbations

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7
Q

acute chrons attack treatments

A

oral corticosteroids +/- aminosalicylates

**elemental diet is nearly as effecitve, but relapse is more likely

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8
Q

when to add abx to chrons

A

metronidazole or ciprofloxacin- perianal dz, fissures or fistulas

**influximab can be used in refractory caes

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9
Q

what is the best option for maintenance therapy for chrons

A

mesalamine

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10
Q

mesalamine adr

A

ulcerative colitis exacerbation, anaphylaxis, angioedema, drug rxn, SJs, interstial neprhitis, all the other itis

Lupus like syndrome

agranulocytosis

aplastic anemia

reye syndrome

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11
Q

malabsorptive disorder w/ chrons dz

A

vit b12, folic acid, vit D

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12
Q

ulcerative coltis

A

generally starts distally, at the rectum, and progresses proximally

disease is continous, skip areas are not seen

onset is generally gradual- also can be abrupt

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13
Q

UC cf

A

tenesmus and bloody, pus-filled D

pain is less common, but may occur in the more severe dz

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14
Q

severe UC CF

A

weight loss, maliase, and fever

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15
Q

toxic megacolon and malignancy are more likely in what?

A

UC

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16
Q

other comlications of UCdz?

A

scleritis, episcleritis, arthritieds, sclerosing cholangitis, and skin manifestations (erythema nodosum and pyoderma gangrenosium)

17
Q

smoking and IBD

A

crohn’s-smokin is bad

smokin is protective in UC

18
Q

how to dx UC

A

abdominal plain -film may show colonic dilation,

best method- sigmoidoscopy

19
Q

what to avoid in UC (acute disease)

A

colonoscopy or barium enema- risk of perforation and toxic megacolo

20
Q

what are the best treatment methods?

A

oral or tolical aminosalicylates ( balsalazide, mesalazine, olsalazine and sulfasalazine) and corticostteroids

21
Q

adr of sulfasalazine

A

anorexia, HA, GI, fever, abnormal LFTs, photosynsitivity, oligospermia, crystalluria, hematuria,cyanosis

22
Q

what is curative in UC?

A

total protocolectomy

23
Q

depth of location in UC>

A

just mucosal