Inflammatory BOWEL Disease Flashcards
chronic inflammation of the bowel which relapse and remit over years
Inflammatory BOWEL Disease (IBD)
characterized by episodes of inflammation limited to the mucosal layer of the colon
Ulcerative colitis
almost invariably involves the rectum, and the extent often involves more proximal portions of the colon in a continuous fashion
Ulcerative colitis
characterized by transmural inflammation and by skip areas of involvement
Crohn disease
may lead to fibrosis and strictures. In any part of the digestive tract.
Crohn disease
Genetic factors
Etiology / Risk factors of IBD
Environmental factors
Etiology / Risk factors of IBD
Common in non-smokers and ex-smokers
Ulcerative colitis
Common in smokers
Crohn disease
Associated with low-residue, high-refined-sugar diet
Crohn disease
Commensal gut microbiota
Environmental factor
Both Ulcerative colitis and Crohn disease
Appendicectomy protects against
Ulcerative colitis
rectal bleeding + diarrhea (with mucus or blood)
Cardinal symptoms of Ulcerative colitis
Some pass pellety stool due to
constipation upper to the inflamed rectum
Cardinal symptoms + Tenesmus
Proctitis Ulcerative colitis