Inflammatory bowel disease

Question 1

Definition of inflammatory bowel disease?

Answer 1

Its name for different types of diseases causing inflammation of GI tract:

Ulcerative Colitis

Crohns Disease

Question 2

Main features of crohns?

Answer 2

N: No blood or mucus
E: Entire GI tract
S: Skip lesions on endoscopy
T: Terminal illeum most affected
S: Smoking is risk factor

Question 3

Main features of Ulcerative colitis features?

Answer 3

C: Continuous inflammation
L: Limited to colon + Rectum
O: Only superficial Mucosa affected
S: Smoking is protective
E: Excrete blood + mucus
U: Use aminosalicylates
P: Primary Sclerosing Cholangitis

Question 4

How to test for inflammatory bowel disease?

Answer 4

Routine bloods for anaemia, infection, thyroid function.

CRP indicates inflammation and active disease

Faecal Calprotectin

Endoscopy

Imaging with ultrasound, CT and MRI.

Question 5

Management of Crohns?

Answer 5

First line = Steroids ( oral predisolone)

Surgery should be done if it effects the distal ileum

Question 6

Management of ulcerative colitis?

Answer 6

First line = Introduce remission

If severe IV corticosteroids

Surgery is possible but patient will be left with a J-pouch

Question 7

Ulcerative colitis definition?

Answer 7

Where ulcers form across lumen of large intestine because of antibodies destroying mucosa. ( autoimmune disease)

Question 8

Crohns disease?

Answer 8

Where body has bacteria which triggers a unregulated inflammation response which destroys cells as well as bacteria. They end up greeting granulomas which destroy cells and ulcers which deeper than just mucosa.

Question 9

How does Crohns appear?

Answer 9

Crohns has a cobblestone appearance.

Question 10

Where does crohns affecct on body?

Answer 10

Right lower quadrant ( illium )

Question 11

Where does Ulcerative Colitis affect on body?

Answer 11

Left lower quadrant ( rectum + colon )