Inflammatory Bowel Disease

Question 1

What are the classifications of IBD?

Answer 1

Ulcerative colitis - colon

Crohn’s disease - anywhere in GI tract

Question 2

What are environmental factors for IBD?

Answer 2

• Diet, smoking, and stress alter microbial flora
• High intake of refined sugars
• Low intake of raw fruit, vegetables, omega-3s, dietary fiber.

Question 3

What drugs are associated with IBD?

Answer 3

• NSAIDs
• Antibiotics
• Oral contraceptives

Question 4

What should we know about a barium enema or swallow?

Answer 4

Adequate nutrition is a must

Question 5

What are systemic complications of IBD?

Answer 5

• MS
• Malabsorption, liver disease, Osteoporosis
• Need routine liver function tests
• Bone density scan baseline and every 2 years

Question 6

What medications contain 5-ASA?

Answer 6

Sulfasalazine (Azulfidine)
Olsalazine (Dipentum)
Mesalamine (Pentasal)
Most effective for UC but used to treat both, administered oral and rectal

Question 7

When should patients not take methotrexate?

Answer 7

When pregnant

Question 8

What is Infliximab (Remicade)?

Answer 8

An Anti-TNF - antitumor necrosis factor agent which induces and maintain remission
Anything that ends with mab is a biological modifier