Inflammatory and Structural Heart Disorders Flashcards
Infection of the inner layer of the heart that usually affects the cardiac valves
Infective Endocarditis (IE)
Pathophysiology of IE?
when blood turbulence within heart allows causative agent to infect previously damaged valves or other endothelial surfaces
Most common causative agents of IE?
- staphylococcus aureus
- streptococcus viridans
Fibrin and platelets adhere to the valve surface forming a lesion called?
Vegetations
Risk Factors of IE (cardiac conditions)?
- Prior endocarditis
- Prosthetic valves
- Valve disease
- Cardiac lesions
- Congenital heart disease
- Pacemakers
- Marfan’s syndrome
- Cardiomyopathy
Risk Factors for IE (Noncardiac)?
- increasing age
- Hospital-acquired bacteremia
- dental procedures
- IV drug abuse
Risk Factors of IE (Procedure-Associated)?
- Intravascular devices
- Dental procedures
- Respiratory procedures
- GI and GU procedures
Clinical manifestations of IE?
- Murmur in most patients (new or changed)
- Heart failure in up to 80% with aortic valve endocarditis
- other manifestations secondary to embolism
- Low grade fever (90%)
- Chills
- Weakness
- malaise
- fatigue
- Anorexia
- Vascular Manifestations
- embolism-organ infarction
Major diagnostic criteria needed for IE confirmation? (need 2 for definitive diagnosis)
- Positive blood cultures (2 drawn 30 min apart)
- New or changed murmur
- Echocardiogram shows intra-cardiac mass or vegetation
Diagnostic tests for IE?
- CXR and ECG can provide more information on extent of disease
- WBC (seriousness of infection)
- Estimated Sedimentation Rate (ESR)
- C-Reactive Protein (CRP)
- Coronary Catheterization/Angiogram (not 1st choice) to see damage of valve
Medication Interventions for IE?
- Antibiotic administration
- Monitor antibiotic serum levels (e.g., peak and trough)
- Subsequent blood cultures
- Monitor renal function
- Fungal and prosthetic valve endocarditis
- Respond poorly to antibiotics
- May need valve replacement
- Prophylactic Treatment
- Antibiotics before dental or invasive procedures
Nursing Interventions for IE?
- Increase activity slowly
- TEDS
- C&DB
- Observe for complications or worsening disease
- Teach
- Risk reduction
- Avoid sick people
- Good nutrition
- Good oral hygiene
- Notify HCP prior to invasive procedures
Complications of IE?
- Dysrhythmias
- Valve dysfunction
- Heart failure
- Sepsis
Most common valves affected by Valvular Heart Disease?
Mitral and Aortic
Cardiac Functional alterations seen in Valvular Heart Disease?
- Stenosis (narrowing)
- Regurgitation (backward flow)
The below are characteristic of?
- Valve orifice is restricted.
- Forward blood flow is impeded.
- A pressure gradient is created across open valve.
Stenosis
What is an incomplete closure of valve leaflets that results in backward flow of blood?
Regurgitation
Most common cause of Mitral Valve Stenosis?
Rheumatic heart disease
Manifestations of Mitral Valve Stenosis?
- Exertional Dyspnea-reduced lung compliance
- Fatigue and palpations (A-fib)
- Murmur
Causes of Mitral Valve Regurgitation?
- MI
- Rheumatic heart disease
- Mitral valve prolapse
Manifestations of
Acute Mitral Valve Regurgitation?
- New systolic murmur
- Pulmonary Edema
Manifestations of Chronic Mitral Valve Regurgitation?:
- may be asymptomatic for years
- Weak, fatigued
- Dyspnea
- palpitations
- Audible S3 sound
- murmur
Complications of Mitral Valve Prolapse?
- Mitral valve regurgitation
- Infective endocarditis
- Sudden death
- Cerebral ischemia
Manifestations of Mitral Valve Prolapse?
- Most patients asymptomatic for life