Heart Failure Flashcards
1
Q
- an abnormal clinical syndrome involving impaired cardiac pumping and/or filling.
- characterized by ventricular dysfunction, reduced exercise tolerance, diminished quality of life, and shortened life expectancy.
A
Heart Failure
2
Q
Heart Failure
A
- an abnormal clinical syndrome involving impaired cardiac pumping and/or filling.
- characterized by:
- ventricular dysfunction
- reduced exercise tolerance
- diminished quality of life
- shortened life expectancy.
3
Q
HF Risk Factors
A
- Hypertension
- Modifiable risk factor
- Properly treated/managed can decrease incidence by 50%
- Coronary artery disease (CAD)
- Myocardial infarction
- Advancing age
- Diabetes
- Cigarette smoking
- Obesity
- High serum cholesterol
4
Q
Precipitating Causes for HF?
A
- Anemia - decreases O2 carrying capacity
- Infection - increases O2 demand
- Hypothyroidism - increases rate of atherosclerosis
- Dysrhythmias - decrease CO, increase workload
- Endocarditis - increase O2 demand, damage vessels
- Pulmonary embolism - increase pressure = pulmonary HTN and decrease CO
- Can be caused by any interference in the normal mechanism regulating CO
5
Q
Most common form
of HF?
A
Left-Sided Failure
6
Q
Effects of Systolic HF?
A
- Reduced EF
- Inability to pump blood forward
- Decreased LV ejection fraction (EF)
- end result = pulmonary congenstion
7
Q
Causes of Systolic HF?
A
- Impaired contractile function
- Increased afterload
- Cardiomyopathy
- Mechanical abnormalities
8
Q
Effects of Diastolic HF?
A
- preserved EF
- Impaired ability of the ventricles to relax and fill during diastole, resulting in decreased stroke volume and CO
- Same end result as systolic failure = pulmonary congestion
9
Q
Causes/Risk factors of Diastolic HF?
A
- left ventricular hypertrophy from:
- hypertension
- older age
- female gender
- diabetes
- obesity
10
Q
Seen in disease states such as dilated cardiomyopathy (DCM)
A
Mixed Heart Failure
- diastolic and systolic
11
Q
Effects of Mixed HF?
A
- Poor EFs (<35%)
- High pulmonary pressures
- Biventricular failure
- Both ventricles may be dilated and have poor filling and emptying capacity
12
Q
Type of HF seen in disease states such as dilated cardiomyopathy (DCM)?
A
Mixed HF
13
Q
Right-Sided Heart Failure
A
- RV fails to pump effectively
- Fluid backs up in venous system
- Fluid moves into tissues and organs
14
Q
Causes of Right-Sided Heart Failure?
A
- Left-sided HF is most common cause
- RV infarction
- Pulmonary Embolism
- cor pulmonale (RV dilation and hypertrophy)
15
Q
Ventricular failure leads to:
A
- Low blood pressure (BP)
- Low CO
- Poor renal perfusion
- Abrupt or subtle onset
- Compensatory mechanisms mobilized to maintain adequate CO
16
Q
The main compensatory mechanisms for Heart Failure?
A
- neurohormonal responses
- renin-angiotensin-aldosterone-system (RAAS)
- SNS
- ventricular dilation
- ventricular hypertrophy (last response)
17
Q
What are Natriuretic peptides?
A
- Counterregulatory Mechanisms in HF
- Atrial natriuretic peptide (ANP),
- b-type natriuretic peptide (BNP) release from ventricles
- Released in response to increased blood volume in heart
- Causes: diuresis, vasodilation, and lowered BP
- Counteracts effects of SNS and RAAS
18
Q
Renal effects of Natriuretic peptides?
A
- increased glomerular filtration rate and diuresis
- excretion of sodium (natriuresis).