Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MED208 Histopathology > inflammation , inflammatory diseases, repair > Flashcards

inflammation , inflammatory diseases, repair Flashcards

1
Q

allows inflammatory cells, plasma proteins, and fluids to exit blood vessel and enter interstitial space

A

inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

true or false
in chronic inflammation, mononucleated cells are the cellular infiltrate

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

characterized by the presence of edema and neutrophils in the tissue

A

acute inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

acute inflammation, cells of innate immunity are responsible. immediate response with limited specificity.
a. 1st statement is true
b. 2nd statement is true
c. both are true
d. both are false

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

_______ is present on cells of innate and addaptive immune system and activated by PAMPs.

A

toll like receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

recognizes LPS of gram neg bacteria

A

CD14

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

arachidonic acid is released from phospholipid cell membrane by phospholipase A2. it blocks cyclooxyrgenase or 5-lipooxygenase.
a. 1st statement is true
b. 2nd statement is true
c. both are true
d. both are false

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

prostaglandins are produced by ________

A

cyclooxygenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

all of the following promotes vasodilation
1. PG
2. histamine
3. serotonin
4. thromboxane

a. 2 only
b. 2,3
c. 1,2,3
d. all of the above

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

complement proteins C3a and C5a produces ________ that promotes vasodilation.

A

histamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mast cells release histamine granules. increase vasodilation of arterioles and increased vascular permeability.
a. 1st statement is true
b. 2nd statement is true
c. both are true
d. both are false

A

c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

which of the following is incorrect?
1. alternative pathway - microbe
2. classical pathway - antibody
3. lectin pathway - MBL

a. only 3
b. 1 and 2
c. 1 and 3
d. NOTA

A

d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

complement proteins that trigger mast cell degranulation

A

C3a and C5a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

chemotactic factor for neutrophils

A

C5a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

opsonin for phagocytosis

A

C3b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

inactivate pro inflammatory protein produced in the liver

A

hageman factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what are the outcomes of acute Inflammation

A
  1. 100% complete resolution
  2. scar
  3. chronic inflammation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

which of the following are stimuli of chronic inflammation
1. persistent infection
2. autoimmune disease
3. foreign materials
4. cancer

a. 123
b. 234
c. 2 and 4
d. 1,3 and 4
e. all of the above

A

E

19
Q

true or false
T cells use TCR complex for antigen surveillance

A

true

20
Q

activation of T cells requires
1. binding of antigen
2. MHC complex
3. additional 2nd signal

a. 1 and 2
b 1 and 3
c. 1 only
d. all of the above

A

d

21
Q

enumerate the 5 cardinal signs off inflammation

A

rubor
tumor
calor
dolor
functio laesa

22
Q

all of the following are key mediators od Rubor and calor except
a. histamine
b. PGs
c. TNFs
d. bradykinin

A

c

23
Q

mediators of tumor
a. histamine
b. tissue damage
c. either
d. neither

A

c

24
Q

T or F
bradykinin and PGE2 are the key mediators of Dolor

A

true

25
Q

surrounded by giant cells and rim of lymphocytes

A

granulomatous inflammation

26
Q

extensive outpouring of watery, low protein. derived from serum or secretions from serial mesothelial cells.

A

serous inflammation

27
Q

excessive discharge or build up of mucus in the nose or throat, associated with inflammation of the mucus membrane.

A

catarrhal inflammation

28
Q

enumerate the changes in cellular growth patterns

A

retrogressive
progressive
degenerative

29
Q

which of the following is capable of retrogressive change
1. agenesia
2. hypoplasia
3. atresia
4. atrophy
5. aplasia
6. hyperplasia

a. 1234
b. 123
c. 1245
d. 12345
e. all of the above

A

d

30
Q

tumor with normal tissue or organ components that are inappropriate to surrounding tissues.

A

teratomas

31
Q

degree of cell differentiation and mitotic activity on histology.
ranges from low grade to high grade or undifferentiated.

A

grading

32
Q

degree of invasion and spread from initial site

A

staging

33
Q

true or false
stage generally has more prognostic value that grade

A

true

34
Q

defined as cessation of cardiopulmonary functions and/or cessation of brain activity

A

death

35
Q

Death occurs when there is deep, irreversible absence of electrical brain activity and complete cessation of the vital functions without the possibility of resuscitation.

A

brain death

36
Q

Complete, persistent and continuous cessation of the vital functions of the brain, heart and lungs which maintain life and health.

A

somatic death

37
Q

stiffening of the body parts

A

rigor mortis

38
Q

begins 2 hours after death: becomes permanent after 8hrs

A

livor mortis

39
Q

low HR, low BP, low RR

A

somatic death

40
Q

cooling of the body

A

algor mortis

41
Q

change in skin color after death

A

palor mortis

42
Q

abnormal new cell growth

A

neoplasia

43
Q

responsible for fever and pain

A

PGE2

44
Q

responsible for bronchospasm

A

b4 c4 d4 e4

MED208 Histopathology (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions