INFLAMMATION Flashcards
What are the 3 inflammatory response of Acute Inflammation?
- Vascular
- Cellular
- Mediators
Define Hemodynamics.
Study of forces in blood circulation
Describe Vascular Stage.
Swell Heat Alter function Redness Pain
What response is vascular change with minor injury?
Transient Response (immediate)
What response is vascular change with serious injury damaging vessels, continuing for days?
Sustained Response (immediate)
What response is vascular change with an increase in capillary permeability for 4-24hrs after injury (sunburn)?
Hemodynamic Response (delayed)
Describe Cellular Stage.
Movement of phagocytic leukocytes into injury area
2 types of leukocytes assist in Acute Inflammation Response are?
Granulocytes
Monocytes
Describe Margination in cellular response to inflammation.
Adhesions of leukocytes to endothelial lining
Describe Pavementing in cellular response to inflammation.
WBC occupy the perphery
Describe Emigration in cellular response to inflammation.
WBC move out of capillary into interstitial space
Describe Chemotaxis in cellular response to inflammation.
Chemical movement of phagocytes to damage site (microbe)
Describe Adherence in cellular response to inflammation.
Phagocyte to the pathogen
Describe Phagocytosis in cellular response to inflammation.
Engulf and degrade bacteria
Explain Inflammatory Mediators.
Produce signs/symptoms - originate from plasma or cell
Describe Acute Inflammation.
Immediate response
Short duration
Self-limiting
Exudation of fluid
Describe Chronic Inflammation.
Develop from progressive acute inflammation
Long duration
Self-perpetuating
Infiltration of macrophages/lymphocytes
Describe Granulomatous Formation.
Mass of macrophages surrounded by lymphocytes to form granuloma
Describe Non-Specific Chronic Inflammation.
Diffuse of macrophages and lymphocytes at injury site (scar)
Define Local Manifestations.
Manifestations of swelling/formation of exudates and ulceration
Explain Serous Exudates.
Plasma entering inflammatory site (blister)
Explain Hemorrhagic Exudates.
Damage to blood vessels - leakage of red blood cells from capillaries
Explain Membraneous/Pseudomembranous Exudates.
Mucous membrane surface development (tonsillitis)
Explain Purulent of Suppurative Exudates.
Contian pus
