CELLULAR ADAPTION Flashcards

1
Q

Explain a ‘Housekeeping Gene’

A

Maintenance of basic cellular function/normal function

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2
Q

Explain a ‘Differentiating Genes’

A

Determines characteristics of a particular cell type

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3
Q

Define ‘Homeostasis’.

A

Organism remaining in certain range to maintain stable function

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4
Q

Define ‘Allostasis’.

A

Organ constantly varies and adjust to maintain stable function

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5
Q

Name the 5 types of Adaptive Cells.

A
  • Atrophy
  • Hypertrophy
  • Hyperplasia
  • Metaplasia
  • Dysplasia
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6
Q

Define ‘Atrophy’.

A

Decreasing cell size from lack of work demands/environmental conditions

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7
Q

Describe ‘Denervation Atrophy’.

A

Disuse in muscles of paralyzed limb

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8
Q

Describe ‘Loss of Endocrine Stimulation Atrophy’.

A

Atrophic change in uterus from loss of estrogen during menopause

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9
Q

Describe ‘Inadequate Nutrition Atrophy’.

A

Seen in malnutrition

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10
Q

Describe ‘Ischemia Atrophy’. (lack of blood flow)

A

Cell decrease size and energy requirements to survive

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11
Q

Define ‘Hypertrophy’.

A

Increasing cell size with increase in tissue mass

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12
Q

Which tissues are common to have Hypertrophy?

A

Skeletal and Cardiac muscle tissue - cannot form more cells by mitotic division

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13
Q

Thickening of organ from abnormal functioning of structure is an example of?

A

Adaptive Hypertrophy

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14
Q

Enlargement of remaining organ/tissue after a portion has been removed is an example of?

A

Compensatory Hypertrophy

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15
Q

Define ‘Hyperplasia’.

A

Increase in number of cells in an organ that are capable of mitotic division

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16
Q

Define ‘Metaplasia’.

A

Reversible change - adult cell type replaced by another cell type - reprogramming of an undifferentiated cell - may predispose to cancerous transformation

17
Q

Define ‘Dysplasia’.

A

Deranged cell growth of a specific tissue - a precursor of cancer