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Patho 1 > Inflammation > Flashcards

Inflammation Flashcards

1
Q

Arachidonic acid metabolites

A

cell wall mediators- second messengers

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2
Q

Leukotrienes

A

Cause vascular permeability and chemotaxis- LOX system

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3
Q

Prostaglandins

A

Pain and vasodilatation- COX pathway

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4
Q

Vasoactive amines

A

performed, quickly released, Basophils and Mast Cells (Histamine) Platlets (serotonin)- increase vasodilation and permeability

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5
Q

Complement system

A

20 proteins- innate and adaptive immunity. Increase vasc. permeability, vasodilation, leukocyte adhesion, chemotaxis, phagocytosis

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6
Q

Cytokines

A

produced by 1 cell type to mediate fxn of different cell type- systemic acute phase reactions

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7
Q

Kinin system

A

increase vasc. perm, sm music contractions, vasodilation, pain

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8
Q

Interleukin 1

A

chemotaxis, fever, histamine, WBC release from bone marrow

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9
Q

Tumor necrosis factor

A

fever, WBC release from bone marrow

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10
Q

Nitric Oxide

A

macrophages- tissue distraction and vasodilation

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11
Q

exudate

A

inflammatory extravascular fluid, SG > 1.020

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12
Q

Exudation

A

escape of fluid- increase vasc perm., protein cells into interstitial tissue- acute inflammatory response

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13
Q

Transudate

A

Ultrafiltrate- low protein content out of vasc., SG 1.010- 1.015

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14
Q

pus

A

purulent (WBCs and bacteria) with parenchymal cell debris and leukocytes

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15
Q

Effusion

A

escape of fluid from anatomical vessels by exudation and rupture

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16
Q

abrasion

A

removal of first layer of dermis- regeneration with out scarring

17
Q

laceration

A

accidental incision (stab wound)

18
Q

incision

A

intentional- scalpal

19
Q

crush

A

destruction of components of inner tissue- destroy vasc. and nerves

20
Q

degloving

A

removal of skin and underlying structures from circular area

21
Q

puncture

A

bacteria deep into skin with little opening

22
Q

avulsion

A

chunk of skin and support structures removed- can’t bring back together

23
Q

bite

A

large defects due to strength of jaw, underlying CT.

Patho 1 (5 decks)

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