Inflammation Flashcards
Type of inflammation?
Anterior/posterior uveitis
Non- granulomatous
Type of inflammation?
Bechet’s disease
Non- Granulomatous
Type of inflammation?
Multiple sclerosis
Non- Granulomatous
Type of inflammation?
Retinal Vasculitis
Non- Granulomatous
Type of inflammation?
Endocrine exophthalmos
Non-Granulomatous
Type of inflammation?
Caseous necrosis of TB
Granulomatous: Zonal type
Type of inflammation?
Chalazion
Granulomatous: Zonal type
Type of inflammation?
Ruptured dermoid cyst
Granulomatous: Zonal type
Type of inflammation?
Reaction to suture material
Granulomatous: Zonal type
Type of inflammation?
Rheumatoid scleritis
Granulomatous: Zonal type
Type of inflammation?
Toxocara
Granulomatous: Zonal type
Type of inflammation?
Sarcoidosis
Granulomatous: Discrete type
Type of inflammation?
Tuberculoid leprosy
Granulomatous: Discrete type
Type of inflammation?
Miliary TB
Granulomatous: Discrete type
Type of inflammation?
Sympathetic Uveitis
Granulomatous: Diffuse type
Type of inflammation?
Juvenille xanthogranuloma
Granulomatous: Diffuse type
Type of inflammation?
Vogt-Koyanagi-Harada Syndrome
Granulomatous: Diffuse type
Type of inflammation?
Toxoplasmosis
Granulomatous: Diffuse type
What is a Russel Body?
What condition is associated with them?
An inclusion in a plasma cell whose cytoplasm is filled and enlarged with eosinophilic structures. The nucleus is eccentric or absent.
Associated with B cell lymphomas
What is Diffuse type granulomatous inflammation?
Epitheliod cells are RANDOMLY distributed against a BG of lymphocytes and plasma cells
What is Discrete type granulomatous inflammation?
Nodules/ Tubercles form due to accumulation of epitheliod or giant cells surrounded by a narrow rim of lymphocytes or plasma cells
What is Zonal type granulomatous inflammation?
Central area of necrosis surrounded by a pallisade of epitheliod cells.
In addition PMNs, langhan’s giant cells and macrophages are in turn surrounded by plasma cells and lymphocytes.
What is the characteristic cell type in Granulomatous inflammation?
The epitheliod cell (derived from macrophages or monocyte) or giant cell (derived from fusion of macrophages)
What are the types of Giant cells and describe their appearance
Langhans’ giant cell—typically found in tuberculosis and shows a homogenous, eosinophilic central cytoplasm and peripheral rim of nuclei
Foreign body giant cell—containing foreign material
Touton giant cell—has a rim of foamy cytoplasm peripheral to a rim of nuclei and is seen in lipid disorders e.g.juvenile xanthogranuloma.
