Inflammation Flashcards

1
Q

This is a common, normal reaction of tissues to injury and is a favorable response of the body to irritants or microorganisms that is a protective/ defensive reaction

A

Inflammation

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2
Q

What will happen if there is no inflammation?

A

a. Wounds will not heal
b. Bacteria and other organisms will flourish and eventually cause the death of the host

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3
Q

What are the 2 factors that determine the degree of response?

A
  1. Severity of the injurious stimuli
  2. Reactive capability of the host
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4
Q

This is a type of injury where there is trauma, tear, laceration

A

Mechanical

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5
Q

Type of injury that produces a burn

A

Thermal or Electrical

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6
Q

Type of injury caused by virus, bacteria, or fungi

A

Biological

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7
Q

Under biological injury, what are the 5 viral lesions?

A
  1. Herpes Simplex
  2. Herpes Zoster
  3. Human Papillomavirus Lesions
  4. Cytomegalovirus
  5. Hairy Leukoplakia and Epstein-Barr Virus
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8
Q

5 cardinal signs of inflammation

A
  1. Rubor: redness
  2. Calor: heat
  3. Tumor: swelling
  4. Dolor: pain
  5. Functio Laesa: loss of function
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9
Q

3 systemic changes

A
  1. Body weakness
  2. Fever
  3. Loss of appetite
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10
Q

6 sources of inflammation

A
  1. Heat
  2. Radiation
  3. Pathogenic organisms
  4. Chemical agents
  5. Trauma
  6. Physical agents
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11
Q

4 components of reaction

A
  1. Damage to the tissues
  2. Alteration
  3. Exudation
  4. Granulation and repair
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12
Q

13 steps

A
  1. Injured tissue
  2. Vasoconstriction
  3. Vasodilation
  4. Release of blood
  5. Stasis
  6. Release of histamine
  7. Blood clotting
  8. Migration of cells
  9. Margination of cells
  10. Pavementation
  11. Phagocytosis
  12. Edema
  13. Fibrinogen is converted to fibrin
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13
Q

4 steps of chemotaxis

A
  1. Migration of cells
  2. Margination of cells
  3. Pavementation
  4. Diapedesis
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14
Q

White blood cells assume peripheral position along the endothelium

A

Margination of Cells

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15
Q

White blood cells adhere to walls of the blood vessel

A

Pavementation

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16
Q

Squeezing out of the cells and moving into the injured area

A

Diapedesis

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17
Q

This is engulfment of foreign bodies

A

Phagocytosis

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18
Q

Ingestion of foreign body

A

Endocytosis

19
Q

Excretion of undigested foreign bodies

A

Exocytosis

20
Q

Lysosome fuses with phagocyte forming?

A

Phagolysome

21
Q

A large strand-like protein that forms a sponge-like mesh

A

Fibrin

22
Q

This walls off the area and is capable of blocking drainage to lymphatic channels

A

Fibrin

23
Q

This is capable of ingesting and destroying some but not all bacteria

A

Neutrophils

24
Q

This can dissolve neutrophil itself if it dies and liquifies local cells of host and insoluble fibrin wall that was laid down

A

Lysosome

25
Q

Localized or walled off collection of pus

A

Abscess

26
Q

Liquefied material containing dead and dying neutrophils and host cell debris and is eliminated by the body

A

Pus

27
Q

These appear after the neutrophils and respond to chemical liberated by injured cells but more slowly

A

Monocytes

28
Q

These are phagocytic cells but are larger and are capable of ingesting larger particles

A

Monocytes

29
Q

Prime function of these cells is to phagocytize foreign materials, dead cells and debris at the site of inflammation

A

Macrophages

30
Q

Considered the second line of defense

A

Macrophages

31
Q

Considered the first line of defense

A

Neutrophils

32
Q

These cells appear later in the inflammatory process and its prime function is to recognize foreign material and to elaborate an immune system

A

Lymphocytes

33
Q

These cells seek out foreign proteins and inactivates them by binding them into antigen-antibody complexes

A

Lymphocytes

34
Q

Another cell involved in antigen-antibody response, particularly relating to allergy

A

Eosinophil

35
Q

These cells has granules that contain enzymes capable of digesting antigen-antibody complexes

A

Eosinophil

36
Q

These cells begin to appear within the first few days of the inflammatory response

A

Fibroblasts and Angioblast Cells

37
Q

Young connective tissue cells that can produce fibers usually collagen

A

Fibroblasts

38
Q

Endothelial cells (normally line blood vessels) that bud and form fresh capillaries

A

Angioblasts

39
Q

Type of repair wherein replacement of injured area with the same tissue occurs

A

Regeneration

40
Q

Type of repair wherein replacement of injured area with another type of tissue occurs

A

Repair with scarring (Fibrosis)

41
Q

Represents dense bundles of collagen fibers that have been produced from the granulation tissue to replace the injured area

A

Scar

42
Q

Why does a scar appear red?

A

Due to increased capillary supply from granulation tissue

43
Q

Why does a scar appear white?

A

Due to dense bundles of collagen

44
Q

Return of tissue to normal state or state of repair with a scar

A

End of Inflammation