Inflammation Flashcards
This is a common, normal reaction of tissues to injury and is a favorable response of the body to irritants or microorganisms that is a protective/ defensive reaction
Inflammation
What will happen if there is no inflammation?
a. Wounds will not heal
b. Bacteria and other organisms will flourish and eventually cause the death of the host
What are the 2 factors that determine the degree of response?
- Severity of the injurious stimuli
- Reactive capability of the host
This is a type of injury where there is trauma, tear, laceration
Mechanical
Type of injury that produces a burn
Thermal or Electrical
Type of injury caused by virus, bacteria, or fungi
Biological
Under biological injury, what are the 5 viral lesions?
- Herpes Simplex
- Herpes Zoster
- Human Papillomavirus Lesions
- Cytomegalovirus
- Hairy Leukoplakia and Epstein-Barr Virus
5 cardinal signs of inflammation
- Rubor: redness
- Calor: heat
- Tumor: swelling
- Dolor: pain
- Functio Laesa: loss of function
3 systemic changes
- Body weakness
- Fever
- Loss of appetite
6 sources of inflammation
- Heat
- Radiation
- Pathogenic organisms
- Chemical agents
- Trauma
- Physical agents
4 components of reaction
- Damage to the tissues
- Alteration
- Exudation
- Granulation and repair
13 steps
- Injured tissue
- Vasoconstriction
- Vasodilation
- Release of blood
- Stasis
- Release of histamine
- Blood clotting
- Migration of cells
- Margination of cells
- Pavementation
- Phagocytosis
- Edema
- Fibrinogen is converted to fibrin
4 steps of chemotaxis
- Migration of cells
- Margination of cells
- Pavementation
- Diapedesis
White blood cells assume peripheral position along the endothelium
Margination of Cells
White blood cells adhere to walls of the blood vessel
Pavementation
Squeezing out of the cells and moving into the injured area
Diapedesis
This is engulfment of foreign bodies
Phagocytosis