Inflammation Flashcards
A protective universal response to tissue damage
Inflammation
Beneficial inflammation is usually for an _______ type of inflammation
Acute
Harmful inflammation is usually for an ______ type of inflammation
Chronic
Beneficial Function of Inflammation
- Contain damage and Isolate injury
- Destroy cause of injury
- Destroy resulting nectrotic cells and tissues
- Prepare tissue for healing and repair
Harmful effects of Inflammation
- Digestion of normal tissues
- Swelling
- Inappropriate inflammatory response
The original 4 Cardinal signs of inflammation
- Rubor
- Calor
- Tumor
- Dolor
5th Cardinal sign of inflammation by Virchow
Functio Laesa
Cardinal sign that causes redness
Rubor
Cardinal sign that causes heat
Calor
Cardinal sign that causes swelling
Tumor
Cardinal sign that causes pain
Dolor
Cardinal sign that causes loss of function
Functio Laesa
Chronic cardinal signs
- Rubor
- Calor
- Tumor
- Dolor
- Functio Laesa
Acute cardinal signs
- Rubor
- Calor
- Tumor
- Dolor
Components of Inflammation:
Initial Response of the immune system
Vasoconstriction
Components of Inflammation:
Increased diameter of blood vessels
Vasodilation
Components of Inflammation:
Increased vascular permeability
Endothelial Activation
Components of Inflammation:
- WBCs enter site of injury and kill organisms and remove debris
Neutrophil Activation
Neutrophil Activation releases what
Chemokines
Sequential Steps of a typical Inflammatory Reaction
- Recognition of Stimulus
- Recruitment of WBCs and proteins to site
- Removal of stimulus
- Regulation of response
- Repair
Short type of inflammation
Acute
Responsible WBCs for Acute inflammation
Neutrophils
Long term type of inflammation
Chronic
Responsible WBCs for Chronic inflammation
Monocytes
Inflammation where there is increase in both Neutrophil and Monocytes
Sub Acute/Chronic
Inflammation only in that one area
Localized
Widespread inflammation and can be that the entire organ or system is affected
Generalized/Systemic
Term used when produced due to inflammation
Exudate
Inflammation according to character of exudate:
Watery and Protein-poor
Serous
Inflammation according to character of exudate:
- Protein Rich
- Blood vessels are opened resulting in escape of proteins
Fibrinous
Inflammation according to character of exudate:
- Mucus and debris
- Common for patients with tuberculosis
Catarrhal
Inflammation according to character of exudate:
Has pus
Suppurative / Purulent
Collection of Pus
Abscess
Inflammation according to character of exudate:
RBC leakage or Leakage of blood
Hemorrhagic
Heat and redness on site of infection
Erythema
Extravasation of liquid portion of blood
Edema
Substances that attracts other immune substances to site of infection
Chemokines
