Inflammation (1) Flashcards

1
Q

What is inflammation?

A

Inflammation is a complex reaction that occurs in vascularised tissues in response to harmful stimulus by bringing cells and molecules from circulation to site of injury.

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2
Q

What are the stimulus for inflammation?

A
  1. Tissue injury such as trauma, cuts
  2. Infectious agent (bacteria, virus)
  3. Exposure to toxins (bee stings)
  4. Foreign bodies (splinters)
  5. Immune reactions (autoimmune disease)
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3
Q

Inflammation is a fine balance in which it can be beneficial but also can be harmful. Describe.

A

little IF restores homeostasis, fights disease and enables wound healing. However, too much IF can result in pathological conditions such as RA, cancer etc..

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4
Q

What are the 5 signs of IF?

A

P: pain, due to chemicals released at nerve endings
R: redness due to increased blood flow
I: immobility due to fluid accumulation
S: swelling due to fluid accumulation
H: heat due to increased blood flow

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5
Q

What are the 2 types of inflammation?

A

Acute and chronic

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6
Q

Describe the 2 types of IF.

A

Acute: rapid onset, short duration, initial response of body to stimuli
Chronic: prolonged IF, slow onset, longer lasting

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7
Q

What is the predominant cell type in acute IF?

A

neutrophils

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8
Q

What is the main aim of acute IF?

A

to remove causative agent and minimize tissue damage. it is a protective response that initiates immune response to promote tissue repair

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9
Q

What are the 2 stages of acute IF?

A

vascular & cellular

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