Infertility in farmed species workshop Flashcards

1
Q

List 3 ways that infertility presents in farm animals

A

Animals that are not (or do not appear to be) cycling at all
Animals are cycling but do not conceive
Animals that conceive but do not maintain pregnancy

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2
Q

If Animals that are not (or do not appear to be) cycling at all
describe how to investigate

A

Rule out poor oestrus detection first (i.e. are these animals truly in anoestrus) –> data and clinical exam
Investigate possible reasons for true anoestrus

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3
Q

If animals are cycling but do not conceive
describe how to investigate

A

Investigate reasons for non-conception including the male animal or AI procedure

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4
Q

If Animals that conceive but do not maintain pregnancy
Describe how to investigate

A

Investigate reasons for foetal/embryonic death

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5
Q

List 6 possible reasons for anoestrus in farm animals

A

failure to observe oestrus
metabolic/ nutritional
uterine infection
pregnancy
cystic ovarian disease
suckling calf at foot

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6
Q

In sheep are infectious or non-infectious causes of infertility most important in sheep

A

infectious

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7
Q

are infectious or non-infectious causes of infertility most important in cattle

A

non-infectious

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8
Q

how does BVD affect fertility

A

causes Early embryonic death (EED) and Ovarian damage
causes long returns to service and reduce conception rates

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9
Q

How does Border disease presentes regarding fertility in sheep

A

increased barren rate

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10
Q

List 3 possible viral causes of infertility in farm species

A

BVD- cattle
Border disease- sheep and goats
IBR- cows

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11
Q

List 4 bacterial and protozoal causes of infertility in farm species

A

Leptospira - cattle (sheep can act as carriers)
Brucella - all ruminants
Campylobacter - cattle and sheep
Tritrichomonas- cattle

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12
Q

What are the effects of brucella

A

poor fertility
epididymitis and orchitis

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13
Q

How does IBR effect reproductive performance

A

temporary ovarian necrosis
follicular degeneration

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14
Q

List 2 special considerations you need to make for maiden heifer when investigating fertility

A

may not have reached puberty
may have repro tract abnormalities- e.g. freemartinism or Mucometra (rare)

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15
Q

List 4 possible effects of campylobacter on the repro tract in cattle/ sheep

A

Endometritis (cattle)
Failure to conceive
Early embryonic death (cattle)
Abortion (sheep and cattle)

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16
Q

Before giving PGF2a to a cow what should you do

A

check for pregnancy

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17
Q

what effect does GnRH have at start of oestrus

A

ovulation in 24-48hrs

18
Q

what effect does GnRH have 10-12 days post-oestrus

A

reinforce CL action - aids progesterone secretion
Induce ovulation
Anti-luteolytic effects- makes CL less sensitive to PGF2a

19
Q

List 4 possible uses of GnRH

A

synch protocols
Treat follicular cysts
Treat anoestrus cows
Ovulation in repeat breeder cows

20
Q

List 6 possible causes of ‘ cycling cows that do not conceive’

A

improper/ incorrect insemination
infectious causes
toxins
metabolic/ nutritional cauases
iatrogenic causes- improper use of hormonal drugs
Sire choice

21
Q

How does PGF2a work

A

Cause luteolysis of CL –> fall in progesterone resulting in FSH and LH release
Only work if CL present

22
Q

at what point is a CL sensitive to PGF2a

A

CL only sensitive to PGF2α between days 5 – 15 of cycle
>17mm diameter on US scan

23
Q

List 5 potential uses of PGF2a

A

Synch protocols
Treat luteal cysts
Induce abortion or parturition
Treat pyometra
Control of breeding and oestrus timing

24
Q

Describe how progesterone works

A

Acts as an exogenous CL –> release progesterone and suppress GnRH release
Dominant follicle develops —> does not ovulate
Removal of device (drop in progesterone) –> LH surge —> ovulation

25
Q

List 5 potential uses of progesterone devices

A

Synch and embryo transfer protocols
Treat cysts
Improvements in oocyte quality
Reduce time to service (seasonal herds)
Repeat breeders

26
Q

Describe how to treat endometritis in cattle

A

PGF2a - may need 2 doses
possibly wash out ???- day after PGF2a when cervix opens - variable results
Recheck on next visit

27
Q

Describe how to treat follicular cysts in cows

A

GnRH or progesterone
Can pop them- but this is risky - there are reports of some animals getting life threatening bleeds and formation of scar tissue that can affect ovary function

28
Q

Describe how to tell the difference between follicular and luteal cysts

A

Luteal cysts= the wall of the cyst is 4-5mm thick, made of luteal tissue so same echogenicity as a CL
Follicular cyst= thin wall

29
Q

Describe how to treat multiple small follicles

A

GnRH or progesterone- could be part of a synch protocol

30
Q

what 2 things can multiple small follicles on both ovaries mean

A

the animal ovulated yesterday
OR
is in true anoestrus

31
Q

What is the calculation to work out fertility efficiency

A

submission rate x conception rate

32
Q

List 4 ways to improve oestrus detection in cattle

A

improve staffing
improved environment
oestrus detection aids
synchronisation protocols

33
Q

List some examples of oestrus detection aids

A

cow worn devices
tail chalk - when rubbed off = has been mounted
Heat patch- change to red is mounted for >3s

34
Q

List 3 ways to make a bull infertile

A

vasectomy
epididymectomy
penile alterations- for venereal diseases- mostly done in US

35
Q

What are the effects of leptospira on reproduction

A

poor fertility and early embryonic death –> may be due to endometrial inflammation

36
Q

can sheep become infected with leptospira

A

yes but they rarely show disease- they are usually carriers

37
Q

What are the effects of tritrichomonas on reproduction

A

early embryonic death
pyometra
endometritis

38
Q

Describe how we can tell the difference between metritis and pyometra (endometritis)

A

pyometra will have a CL
metritis occurs shortly after parturition- cow systemically unwell

39
Q

what size are follicular cysts

A

over 25mm

40
Q

what does ineffective oestrus detection lead to

A

a low submission rate and subsequent low fertility efficiency

41
Q

what is the submission rate calculation

A

(number of cows actually bred / number of cows eligible to be bred ) x100