Infertility and Abortion Flashcards

1
Q

This is the probability of ahcieving pregnancy in one menstrual cycle

A

fecundability

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2
Q

What is an accurate descriptor/definition of fertility?

A

fecundability

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3
Q

For 35 and younger, when do you evaluate for infertility?

A

after 12 mo

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4
Q

For women 35 and older, when do you evaluate for infertility?

A

after 6 mo

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5
Q

This is the inability to conceive entirely

A

primary infertility

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6
Q

this is the inability to conceive after previous fertility

A

secondary infertility

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7
Q

A ______ is the fastest and first evaluation of potential male infertility

A

semen analysis

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8
Q

semen analysis requires ____ days of abstinence and ___ samples 1-2 weeks apart

A

2-7 days

2 samples 2 weeks apart

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9
Q

MC congenital abnormality for men?

A

Klinefelter

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10
Q

3 MC causes of anovulation…

A

PCOS
Thyroid
hyperprolactinemia

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11
Q

What medication causes elevated prolactin?

A

risperidone

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12
Q

Which thyroid conditions can disrupt normal ovulation?

A

hypo and hyper

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13
Q

If persistently elevated prolactin, what should be ordered?

A

MRI for pituitary adenoma

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14
Q

hyperprolactinemia requires ______ for dx

A

second blood draw

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15
Q

Medical tx for hyperprolactinemia…

A

bromocriptine (pregnancy safe)

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16
Q

3 drugs that can be taken for PCOS

A

provera
metformin
clomiphene

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17
Q

Pregnancy safe hyperthyroid med…

A

PTU

18
Q

pregnancy safe hypothyroid med…

A

levothyroxine

19
Q

which ovulation induction med?

SERM

A

clomiphene

20
Q

which ovulation induction med?

aromatase inhibitor
becoming 1st line

A

letrozole

21
Q

Serious side effect of clomiphene and letrozole (ovulation induction meds)

A

ovarian hyperstimulation (thrombosis)

22
Q

Two tubal factors for female infertility…

A

occluded oviduct

insult/surgery

23
Q

What diagnostic can rule out tubal factor infertility?

A

hysterosalpingogram

24
Q

HSG evaluates for tubal _____ not ____

A

tube patency not function

25
Q

is surgical repair recommended for tubal factors?

A

no

26
Q

recommended tx for tubal factors…

A

IVF

27
Q

Female infertility: 2 important questions in HPI

A

regular cycles?

intercourse frequency?

28
Q

Most abortions occur prior to what week?

A

13

29
Q

Medical abortion is indicated up to ___ days of gestational age

A

70 days

30
Q

This is the most common complication of pregnancy…

A

spontaneous abortion

31
Q

spontaneous abortion occurs prior to what gestational age?

A

20 weeks

32
Q

Workup for SAB

A

CBC
Rh type
HCG quant
Pelvic/transvaginal US

33
Q

MC Cause of spontaneous abortion?

A

abnormal karyotype

34
Q

Rh negative in presence of SAB requires…

A

rhogam injection

35
Q

What type of SAB?

retention of part/all products of conception

A

incomplete

36
Q

What type of SAB?

closed cervical os

Bleeding despite (+) urine preg

A

threatened

37
Q

What type of SAB?

open cervical os

(+) bleeding

A

inevitable

38
Q

what type of SAB?

absent heartbeat

no bleeding

cervix closed

A

missed abortion

39
Q

recurrent abortion is ____ or more abortions prior to 20 weeks

A

3+

40
Q

Recurrent abortion workup

A
karyotype both parents
karyotype of embryo
luteal phase progesterone
antiphospholipid Ab
lupus workup
uterine cavity eval