Infertility and Abortion Flashcards
This is the probability of ahcieving pregnancy in one menstrual cycle
fecundability
What is an accurate descriptor/definition of fertility?
fecundability
For 35 and younger, when do you evaluate for infertility?
after 12 mo
For women 35 and older, when do you evaluate for infertility?
after 6 mo
This is the inability to conceive entirely
primary infertility
this is the inability to conceive after previous fertility
secondary infertility
A ______ is the fastest and first evaluation of potential male infertility
semen analysis
semen analysis requires ____ days of abstinence and ___ samples 1-2 weeks apart
2-7 days
2 samples 2 weeks apart
MC congenital abnormality for men?
Klinefelter
3 MC causes of anovulation…
PCOS
Thyroid
hyperprolactinemia
What medication causes elevated prolactin?
risperidone
Which thyroid conditions can disrupt normal ovulation?
hypo and hyper
If persistently elevated prolactin, what should be ordered?
MRI for pituitary adenoma
hyperprolactinemia requires ______ for dx
second blood draw
Medical tx for hyperprolactinemia…
bromocriptine (pregnancy safe)
3 drugs that can be taken for PCOS
provera
metformin
clomiphene
Pregnancy safe hyperthyroid med…
PTU
pregnancy safe hypothyroid med…
levothyroxine
which ovulation induction med?
SERM
clomiphene
which ovulation induction med?
aromatase inhibitor
becoming 1st line
letrozole
Serious side effect of clomiphene and letrozole (ovulation induction meds)
ovarian hyperstimulation (thrombosis)
Two tubal factors for female infertility…
occluded oviduct
insult/surgery
What diagnostic can rule out tubal factor infertility?
hysterosalpingogram
HSG evaluates for tubal _____ not ____
tube patency not function
is surgical repair recommended for tubal factors?
no
recommended tx for tubal factors…
IVF
Female infertility: 2 important questions in HPI
regular cycles?
intercourse frequency?
Most abortions occur prior to what week?
13
Medical abortion is indicated up to ___ days of gestational age
70 days
This is the most common complication of pregnancy…
spontaneous abortion
spontaneous abortion occurs prior to what gestational age?
20 weeks
Workup for SAB
CBC
Rh type
HCG quant
Pelvic/transvaginal US
MC Cause of spontaneous abortion?
abnormal karyotype
Rh negative in presence of SAB requires…
rhogam injection
What type of SAB?
retention of part/all products of conception
incomplete
What type of SAB?
closed cervical os
Bleeding despite (+) urine preg
threatened
What type of SAB?
open cervical os
(+) bleeding
inevitable
what type of SAB?
absent heartbeat
no bleeding
cervix closed
missed abortion
recurrent abortion is ____ or more abortions prior to 20 weeks
3+
Recurrent abortion workup
karyotype both parents karyotype of embryo luteal phase progesterone antiphospholipid Ab lupus workup uterine cavity eval