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Gi > Infective Gastroenteritis > Flashcards

Infective Gastroenteritis Flashcards

1
Q

Risk factors for severe gastroenteritis

A
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2
Q

Symptoms of gastroenteritis

A
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3
Q

Types of infections

A
  1. Non inflammatory (enterotoxin of adherence/superficial invasion
    • ​​affects epithelial function causing massive secretion of electrolytes
    • cells look normal under microscopy
  2. Inflammatory disease
    1. ​Cytotoxin
      • ​​damages cell
    2. Direct invasion of intestinal epithelium

​

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4
Q

Non inflammatory infection

organisms responsible

A
  • vibrio cholera
  • E coli
    • ETEC
    • EPEC
    • EAEC
  • Clostridium perfringes
  • Bacilius cereus
  • staph aureus
  • giardia lamblia
  • rotavirus
  • norovirus
  • Crptospridium species
  • microsporidia
  • cyclospora spp
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5
Q

Cytotoxin inflammatory disease

organisms

A
  • Entamoeba histolytica
  • C defficle
  • shigells spp
  • EHEC
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6
Q

Direct invaders

organisms

A
  • Salmonella spp
  • yersinia enterocolitica
  • campylobacter spp
  • shigella spp
  • EIEC
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7
Q

Shigella epidemiology

not food poisoning

A
  • Humans are only host
  • feco oral therefore with dofect contact with infected person
  • low infective dose (50 bacteria)
    • therefore easily transmitted in corwded places like jails and institutions
  • food is occasionally a vector
  • toilet seats
  • developed world
    • young children
    • S. flexinari and sonii
  • developing world
    • children and adults
    • S. dystentriae and boydii
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8
Q

Shigella

clinical

A
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9
Q

Shigella

complications

A
  • dehydration
  • rf
  • toxic dilaton and perforation
  • HUS
    • S. DYSENTERIAE
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10
Q

Salmonella epidemiology

typical food poisoning

non toxigenic

NON TYPHOID

A
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11
Q

Salmonella clinical presentation

A
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12
Q

Salmonella complications

A
  • septecemia
  • osteomyelitis in sickle cell pt
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13
Q

Camylobacter epidemiology

typically food poisoning

non toxigenic

A
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14
Q

Camylobacter

‘clinically

A
  • Ip 2-5 days
  • Severe diarrhea with blood and pus
  • fever and abdominal pain
  • may mimic appemdecitis
  • last 5-7 days
  • GBS
  • reactive arthritis
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15
Q

Clostridium perfringes epidemiology

typical food poisoning

alpha toxin

A
  • Anaerobic
  • red meat
  • ip 1-4 days
  • abdominal pain
  • explosive diarrhea
  • self limiting
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16
Q

Vibrio cholerae epidmeiology

not typically food poisoning

toxigenic

A
  • Humans are host
  • water and food contaminated with bacteria
  • O1 and O139 cause epidemics
17
Q

V cholerae

clinical

A
18
Q

Staph aureus epidemiology

typically food poisoning

toxigenic

enterotoxin

A
19
Q

Staph aureus

‘clinical

A
20
Q

Clostridium defficile epidemiology

not food poisoning

A
21
Q

Clostridium difficile

clinical

A
22
Q

Bacillus cereus

typically food poisoning

toxingenic

A
23
Q

E coli

A
24
Q

EPEC

A
25
Q

ETEC

A
26
Q

VTEC

A
  • HEMORRHAGIC colitis
  • HUS
    • O157H57 with ground beef
  • aka hemorrhagic
  • sevre bloody diarrhea
  • toxin similar to shigella
27
Q

EIEC

A
  • Shigella like toxin
  • invasion of mucosa
  • dairrhea with blood and pus
28
Q

Yersenia enterocolitica

A
29
Q

Clostridium botulinum

A
30
Q

Vibrio parahyemplyticus

A
31
Q

Listeria

A
32
Q

Giardia lamblia

A
  • worldwide
  • feco oral
  • water contaminated with cyst
  • self limiting
  • stool microscopy
  • METRONIDAZOLE
33
Q

Cryptosporidium parvum

A
  • Animals and men
  • cysts by direct contact with animals or infected ppl
  • water contaminated
  • mild diarrhea
  • severe if immunocompromised
34
Q

Entameba histolytica

A

Dysentry

Gi (5 decks)

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