infectious processess

Question 1

what is the patho of HSV

Answer 1

• virus persists in latent form in trigeminal (dorsal) nerve and other ganglia
• virus contact with skin and mucous membranes

Question 2

what is the etiology of HSV?

Answer 2

HSV1 - above the waist
HSV2 - genitals

Question 3

risk factors of HSV?

Answer 3

stress, common in recurrent lesions

Question 4

clinical manifestations of HSV?

Answer 4

• tingling/burning.
• followed by pustules, ulcers, vesicles and erythema.
• pain is common.

Question 5

how long will it take for HSV-1 to heal?

Answer 5

10-14 days

Question 6

how is HSV diagnosed?

Answer 6

blood testing, swab sample, tzank smear

Question 7

treatment for HSV?

Answer 7

no cure. only can be managed with analegsics for inflammation & antivirals to decrease duration of outbreak

Question 8

what is the patho for herpes zoster (shingles)

Answer 8

• an acute localized inflammatory disease of dermatomal segment of skin
• vesicles develop with redness along the dorsal root ganglia

Question 9

etiology if zoster?

Answer 9

caused by the same herpesvirus that causes varicella

Question 10

where is zoster present?

Answer 10

sensory dorsal root ganglia

Question 11

what happens during the zoster virus attack?

Answer 11

-shingles reactivated, virus travels from ganglia to the skin of corresponding dermatome
- results from reactivation of latent virus

Question 12

zoster diagnosis?

Answer 12

rash

Question 13

clinical manifestations of zoster?

Answer 13

• vesicles with erythematous bases, lesions, paraesthesia (numbness and tingling)
• pain
• typically unilateral

Question 14

complication with zoster?

Answer 14

• postherpetic neuralgia characterized by recurring pain after rash.
• can presist for months to years, most common in > 60 years old