Infectious Diseases Flashcards
Malaria: Most important parasitic disease in man
Malaria
Malaria: 72 hour cycle
P. Malariae
Malaria: Only Malignant Tertian
P. Falciparum
Malaria: RBC Preference: All ages
P. Falciparum
Malaria: RBC Preference: Old
P. Malariae
Malaria: Highest Parasitemia
P. Falciparum
Malaria: Lowest Parasitemia
P. Malariae
Malaria: 0 Merozoites
P. Falciparum
Malaria: Banana-Shaped Gametocytes
P. Falciparum
Malaria: Large & Round Gametocytes
P. Vivax
Malaria: Compact Gametocytes
P. Malariae
Malaria: Small & Round Gametocytes
P. Ovale
Malaria: Recrudescence
P. Falciparum & P. Malariae
Malaria: Relapse
P. Vivax & P. Ovale
Malaria: Prone to Drug Resistance
P. Falciparum
Malaria: Recurrence of symptoms after 2-4 week abatement
Recrudescence
Malaria: Return of disease after apparent cessation (1-6 months) due to reactivation of hypnozoites
Relapse
Malaria: Screen for presence of Malarial organisms
Thick smears
Malaria: Species identificaction
Thin smears
Malaria: Highest yield of thick and thin smears (Timing)
During fever or 2-3 hours after peak
Malaria: What do you call the Punctate granulation present in RBCs invaded by P. Ovale and P. Vivax
Schuffner dots
Malaria: Coarse granulations present in RBCs invaded by P. Falciparum
Maurer dots
Malaria: Fine dots present in RBCs invaded by P. Malariae
Ziemann dots
Malaria: Malarial or Durck granulomas
Cerebral Malaria
Malaria: Acute Renal Failure in Malaria
Blackwater Fever
Malaria: Septic Shock in Malaria
Algid Malaria
Malaria: Endemic: Palawan?
Yes
Malaria: Endemic: Mindoro?
No
Malaria: Endemic: Cebu?
No
Malaria: Endemic: Quezon?
No
Malaria: Endemic: Abra?
No
Malaria: Endemic: Kalinga?
Yes
Malaria: Endemic: Apayao?
Yes
Malaria: Endemic: Nueva Ecija?
No
Malaria: Endemic: Agusal Del Sur?
Yes
Malaria: Endemic Provinces?
Palawan, Kalinga, Apayao, Ifugao, Agusan del Sur
Typhoid Fever: Stepwise Fever, Relative Bradycardia, Bacteremia, Anorexia, Malaise
Week 1
Typhoid Fever: Abdominal Symptoms, Rose Spots, Jaundice, Hepatosplenomegaly
Week 2
Typhoid Fever: Bleeding, Ileitis, Pneumonia
Week 3
Typhoid Fever: Recovery or Death
Week 4
Typhoid Fever: Week 1
Blood
Typhoid Fever: Week 2
Urine
Typhoid Fever: Rose Spots
Week 2
Typhoid Fever: Stool
Week 3
Typhoid Fever: Week 4
Bone Marrow (Always)
Typhoid Fever: Incubation period of Typhoid
5-21 days
Typhoid Fever: Week of Complications (Typhoid)
Week 3
Typhoid Fever: Antibiotics used in the Philippines
Ceftriaxone (resistant), Quinolones (susceptible)
Typhoid Fever: Eradice Salmonella carriage in the GB
Ampicillin
Leptospirosis : Most severe form
Weil Syndrome
Leptospirosis: Most common cause of death
Massive Pulmonary Hemorrhage
Schistosomiasis: Penetrates Skin
S. Japonicum
Schistosomiasis: Affects Liver
S. Japonicum, C. Sinensis
Schistosomiasis: Affects Lung
P. Westermani
Schistosomiasis: Raw Crab Ingestion
P. Westermani
Schistosomiasis: Raw Fish Ingestion
C. Sinensis
Schistosomiasis: Intermediate Host: S. Japonicum
Snail
Schistosomiasis: Intermediate Host: P. Westermani
Snail and Crab
Schistosomiasis: Intermediate Host: C. Sinensis
Snail and Fish
Schistosomiasis: Treatment
Praziquantel
Schistosomiasis: Systemic Hypersenstivity in Schistosomiasis
Katayama Fever
Schistosomiasis: Resembles Serum Sickness
Katayama Fever
Schistosomiasis: Endemic: Sorsogon
Yes
Schistosomiasis: Endemic: Samar
Yes
Schistosomiasis: Endemic: Leyte
Yes
Schistosomiasis: Endemic: Occidental Mindoro
No
Schistosomiasis: Endemic: Oriental Mindoro
Yes
Schistosomiasis: All of Mindanao Except
Misamis Oriental
Anaerobic, Gram-Positive, Spore-Forming Rod
C. Tetani
Resembles a Tennis Racket
C. Tetani
Negri Bodies
Rabies
Rabies Fatality
Early Brainstem Dysfunction
Presence of Microbes or Toxins in Blood
Septicemia
2 or more of the ff: Fever, Tachypnea, Tachycardia, Leukocytosis
SIRS
SIRS + Positive Blood Culture
Sepsis
Sepsis with hypotension despite ADEQUATE fluid resuscitation
Septic Shock
Sepsis that does not respont to fluids or pressors
Refractory Septic Shock
Dysfunction of more than one organ, requiring interention to maintain homeostasis
MODS
SIRS Criteria: Fever
> 38 or
SIRS Criteria: Tachypnea
> 24
SIRS Criteria: Tachycardia
> 90
SIRS Criteria: Leukocytosis
> 12 or 10% Bands
Vancomycin
Bactericidal
Fluoroquinolones
Bactericidal
Penicillins
Bactericidal
Aminoglycosides
Bactericidal
Metronidazole
Bacteriostatic
Erythromycin
Bacteriostatic
Clindamycin
Bacteriostatic
Sulfamethoxazole
Bacteriostatic
Trimethoprim
Bacteriostatic
Tetracycline
Bacteriostatic
Chloramphenicol
Bacteriostatic
Sulfamethoxazole
Bacteriostatic
Static + Static
Cidal