Infectious diseases Flashcards
From which age can influenza vaccination be administered?
A) 6 months
B) 12 months
C) 5 years
D) 18 years
A) 6 months
Against which infectious disease is not post-exposure prophylactic vaccination available?
A) Hepatitis A
B) Tetanus
C) Varicella
D) Pertussis
D) Pertussis
In case of injury with suspected tetanus infection, in addition to tetanus toxoid vaccination, the injured person should be given passive immunisation if the wound is severely damaged or contaminated with soil, a foreign body is present, in case of head injury, shock, bleeding, severe burn injury, radioactivity and if the time elapsed since the last vaccination of the person receiving the booster dose is more than:
A) 3 years
B) 5 years
C) 10 years
D) in all cases, the injured person must be given passive immunisation, regardless of the time elapsed since the previous tetanus vaccination
C) 10 years
Minimum interval between therapeutic intravenous immunoglobulin (IVIG) and live virus vaccine is:
A) 4 weeks
B) 3 months
C) 11 months
D) 2 years
C) 11 months
Contraindications to vaccination, EXCEPT:
A) Convulsions in the family history
B) Febrile illness
C) Vaccination of a pregnant woman with a live virus vaccine
D) Suspected or existing congenital immunodeficiency
A) Convulsions in the family history
Administered as an oral vaccine:
A) DTaP
B) DTap + IPV + Hib
C) Varilrix/Varivax
D) Rotarix
D) Rotarix
Effective antibiotic against Pseudomonas aeruginosa, EXCEPT:
A) piperacillin / tazobactam
B) ceftazidime
C) ciprofloxacin
D) cefotaxime
D) cefotaxime
Common pathogens in endocarditis, EXCEPT:
A) Staphylococcus aureus
B) Alpha-hemolytic Streptococci
C) Enterococcus faecalis
D) Listeria monocytogenes
D) Listeria monocytogenes
Antibiotic therapy expected to be effective against community-acquired MRSA infection:
A) amoxicillin/clavulanic acid
B) cefixime
C) co-trimoxazole
D) cefprozil
C) co-trimoxazole
The minimum duration of intravenous treatment for paediatric osteomyelitis should ideally be:
A) intravenous treatment is not recommended
B) 3-4 days
C) 3-4 weeks
D) 6 weeks
B) 3-4 days
Extrapulmonary manifestations of Mycoplasma pneumoniae may include:
A) acute disseminated encephalomyelitis (ADEM)
B) hepatitis
C) erythema multiforme
D) A, B and C are all correct
D) A, B and C are all correct
A 13-month-old baby has monosymptomatic fever for 3 days. After resolution of fever maculopapular rash appears on the neck and torso which spread onto the limbs. The baby is in relatively good general condition throughout the course of the disease; appetite, fluid intake is not reduced. What is the most likely diagnosis?
A) Varicella
B) Exanthema subitum
C) Meningococcemia
D) Scarlet fever
B) Exanthema subitum
Which therapy would you choose in RSV bronchiolitis?
A) dexamethasone
B) inhalatory ribavirin
C) supportive care only
D) remdesivir
C) supportive care only
A 7-year-old child is hospitalised for 5 days with fever and bloody diarrhoea. Which pathogen is unlikely based on the symptoms?
A) Campylobacter jejuni
B) Salmonella enterica enteritidis
C) EHEC
D) Rotavirus
D) Rotavirus
For a 3 years old, febrile child, who is returning from a tropical vacation, which test should always be performed?
A) Dengue virus detection
B) Thick and thin smear
C) Stool culture
D) Pharyngeal swab culture
B) Thick and thin smear
After camping in the forest a 7 years old child is presented with a 10 cm diameter ring-shaped, non-painful, mildly pruritic erythematous macule on the back of his neck. What antibiotic therapy should be recommended?
A) amoxicillin
B) doxycycline
C) azithromycin
D) streptomycin
A) amoxicillin
A 18 month old child experiences sore throat, fever for 2 days, and loss of appetite. On physical examination, you notice enlarged tonsils with white patches and nodules. Which empirical antibiotic treatment do you recommend?
A) amoxicillin
B) amoxicillin-clavulanic acid
C) cefixime
D) you don’t recommend antibiotic therapy
D) you don’t recommend antibiotic therapy
A patient who came from Ukraine with unknown vaccination status temporarily gets better after a few days of fever, headache, and gastroenteric symptoms. After a few fever-free days, headache, neck and spinal pain, vegetative symptoms, and ascending paralytic flaccid paralysis appear. Which pathogen is essential to rule out?
A) Listeria monocytogenes
B) West Nile virus
C) Clostridium tetani
D) Poliovirus
D) Poliovirus
A few hours after Christmas dinner, all members of a family (except the oldest sibling who is vegetarian) of a 9 years old patient are presented with vomiting and diarrhoea. How would you manage your 9 years old patient?
A) Start antibiotic therapy effective against Staphylococcus aureus, as it is the most likely pathogen
B) Start antibiotic therapy effective against Bacillus cereus, as it is the most likely pathogen
C) Put the patient in epidemiological isolation
D) If necessary initiate parenteral fluid replacement therapy
D) If necessary initiate parenteral fluid replacement therapy
HIV infection can be transmitted through the following body secretions, EXCEPT
A) breast milk
B) blood
C) saliva
D) semen
E) vaginal secretions
C) saliva
An 8 months old patient is referred to the emergency department with constipation, acute-onset hypotension and ptosis. An anamnesis recording reveals that 1 day earlier he consumed honey for the first time in his life. Which pathogen’s role is most likely?
A) Trichuris trichiura
B) Poliovirus
C) Neisseria meningitidis
D) Clostridium botulinum
E) Streptococcus agalactiae
D) Clostridium botulinum
What are TORCH pathogens?
A) Toxoplasma gondii, “Others”, Rubella Virus, Cytomegalovirus, Herpes Simplex Viruses
B) Toxoplasma gondii, “Others”, Rubella Virus, Chlamydia spp., Herpes Simplex Viruses
C) Toxoplasma gondii, “Others”, Rubella Virus, Chlamydia spp., Human Papilloma Viruses
D) Toxoplasma gondii, “Others”, Rubella Virus, Chlamydia spp., Human Immunodeficiency Virus
A) Toxoplasma gondii, “Others”, Rubella Virus, Cytomegalovirus, Herpes Simplex Viruses
Complications of intrauterine Zika-virus infection may include:
A) subacute sclerosing panencephalitis
B) microcephaly
C) chorioretinitis
D) saddle nose
B) microcephaly
Peptidoglycan and glycopeptide. What are these?
A) antiretroviral drugs
B) component of certain cells and an antibiotic group
C) oral antidiabetics
D) antimycoticums
B) component of certain cells and an antibiotic group
Which viruses from the list below can cause arthritis quite frequently?
A) HIV, VZV
B) virus HSV, measles
C) Yellow fever virus
D) Human parvovirus B19, rubella virus
D) Human parvovirus B19, rubella virus
Which ones are the typical pathogens in neonatal infection?
A) S. pyogenes, H. influenzae
B) S. agalactiae, E. coli
C) S. aureus, VZV
D) S. pneumoniae, M catarrhalis
E) CONS, K. oxytoca
B) S. agalactiae, E. coli
Generally, how long a patient with chickenpox is infectious?
A) 3-4 days
B) 14-21 days
C) 6-7 days
D) longer than 21 days
E) 14 days
C) 6-7 days
Which one is the most frequent agent causing acute hepatitis all over the world?
A) EBV
B) HAV
C) HEV
D) Ethyl alcohol
E) CMV
C) HEV
Which virus does not belong to the herpesviridae family?
A) VZV
B) EBV
C) HHV7
D) WNV
E) CMV
D) WNV
During the first week of April a 2 months old baby was taken to your surgery who was born at 29 weeks of gestation and has been suffering from BPD. The infant was discharged from NICU a week ago. What vaccination would you recommend for the baby to have beside the scheduled ones?
A) 1 dose influenza split vaccine in autumn
B) 1 dose of inactivated influenza vaccine immediately
C) no vaccine is recommended
D) 2 doses of split vaccine in autumn 1 month apart
E) 2 doses of inactivated influenza vaccine, first one urgently, second one in autumn
D) 2 doses of split vaccine in autumn 1 month apart
Patients with the following risk factors should receive PCP prophylaxis as they are at high risk for PCP, EXCEPT:
A) patients with acute lymphocytic leukaemia
B) patients with certain primary immunodeficiencies like SCID, hyper IgM syndrome
C) solid organ transplant recipients, often for at least 6 months to one year following transplantation
D) asthmatic patients who receive 2 mg/kg prednisolone for 5 days during acute attack
D) asthmatic patients who receive 2 mg/kg prednisolone for 5 days during acute attack
Which one was the most frequent bacterial diarrheal disease over the past years in Hungary?
A) yersiniosis
B) salmonellosis
C) campylobacteriosis
D) shigellosis
C) campylobacteriosis
Patient suffering from one of the following diarrheal diseases should be isolated on Infectology Ward:
A) Salmonellosis
B) Campylobacteriosis
C) Clostridioides difficile infection
D) None of them
D) None of them
One of the following clinical pictures is not related to any of human herpes viruses:
A) Mononucleosis infectiosa
B) Erythema infectiosum
C) Varicella
D) Burkitt-lymphoma
E) Exanthema subitum
B) Erythema infectiosum
Most frequent cause of serous meningitis with a cumulative number of cases in the summer and in early autumn:
A) Neisseria meningitidis
B) Non-polio enterovirus
C) Leptospira interrogans
D) West Nile virus
E) Herpes simplex virus 1 and 2
B) Non-polio enterovirus
Congenital CMV infection can be confirmed with one of the following laboratory test:
A) Maternal CMV serology
B) Baby’s CMV serology is enough to confirm the diagnosis
C) CMV PCR test on baby’s urine sample during the first three weeks of life
D) CMV PCR test on maternal blood sample
C) CMV PCR test on baby’s urine sample during the first three weeks of life
Pregnant woman around 34 weeks of gestation had a flu-like illness. Couple of days later she gave birth to a preterm newborn with a birth weight of 2200 gs. Soon after birth the baby develops symptoms of RDS. Examining the placenta on the foetal side small white nodes can be seen. Newborn had neutropenia and thrombocytopenia. In gastric aspiration with Gram stain Gram-positive rods can be detected. What is the most likely causative agent from the list below?
A) C. botulinum
B) E. coli
C) Group B Streptococcus
D) L. monocytogenes
E) S. aureus
D) L. monocytogenes
A 4 year old girl has been taken to GP surgery with fever (38.8°C) and cough. There is no severe illness in her medical history, on physical examination symptoms of URTI can be found. Chest x-ray shows a 5 x 6 cm inhomogeneous consolidation on the right side in the middle lobe. Which antibiotic would you choose from the list below to treat the patient?
A) amoxicillin
B) cefixime
C) oxacillin
D) tazocin
E) ceftriaxone
A) amoxicillin
A patient attended at A&E with paleness, oedema and reduced urine output a week after he had recovered from bloody gastroenteritis. What could be the diagnosis?
A) Hemolytic uremic syndrome
B) Salmonella sepsis
C) Reye syndrome
D) Invasion of dysenteric toxin
E) Clostridioides difficile infection
A) Hemolytic uremic syndrome
How would you manage an otherwise healthy patient with Salmonella gastroenteritis?
A) Ampicillin treatment
B) Electrolyte and fluid substitution
C) Sumetrolim treatment
D) Reasec tablet (antimotility agent)
E) Torecan suppository (antiemetic)
B) Electrolyte and fluid substitution
Which infection from the forthcoming ones can mimic acute appendicitis causing mesenteric lymphadenitis?
A) Campylobacter jejuni infection
B) Yersinia enterocolitica infection
C) Salmonella sp. infection
D) Shigella infection
E) Rotavirus infection
B) Yersinia enterocolitica infection
Your patient went hiking to the hills and 2 weeks later complained of flu-like symptoms. Following a couple of asymptomatic days he developed fever again accompanied by strabism, ataxia and paralysis in his shoulder. What could be the diagnosis?
A) Lyme disease
B) Epidemic meningitis
C) Lymphocytic choriomeningitis
D) Tick-borne encephalitis
E) Guillain-Barré syndrome
D) Tick-borne encephalitis
Having this condition increases the risk of Candida infection in the highest degree:
A) atopic/allergic diseases in anamnesis
B) birth weight less than 2000 gs
C) immunosuppressed condition
D) indwelling bladder catheter
E) tonsillectomy
C) immunosuppressed condition
A 6 year old boy has been brought to GP practice by parents with a 3 days history of high temperature (>39°C), malaise and vomiting. Fever is difficult to control. He has taken paracetamol 4 times a day and he also had two doses of sulfametoxazol/trimethoprime. Today he developed a widespread rash. On physical examination itchy, diffuse, pinpoint maculopapular rash can be seen which is more marked in the groin and axilla. Bilateral red cheeks are accompanied by circumoral pallor. White strawberry tongue and exudative tonsillopharyngitis are present with spotted redness on the soft palate. Palms and soles are not red and the hand is not oedematous. Which do you think is the most likely illness?
A) Measles
B) Rubella
C) Scarlet fever
D) Kawasaki disease
E) Exanthema subitum
C) Scarlet fever
What is the first line treatment in case of scarlet fever?
A) penicillin
B) third generation cephalosporin
C) second generation cephalosporin
D) first generation cephalosporin
E) erythromycin
A) penicillin
Which one of the forthcoming infections is followed by exuberant desquamation mainly on the palms and the soles?
A) scarlet fever
B) exanthema subitum
C) erythema infectiosum
D) rubella
E) measles
A) scarlet fever
A 6 year old boy presents with vomiting, hepatomegaly and coma soon after varicella infection. What illness do you think of?
A) Kawasaki disease
B) Reye syndrome
C) VZV hepatitis
D) Still’s disease
E) Septic shock
B) Reye syndrome
What age below tetracycline should not be used because of the risk of tooth discoloration?
A) 3 years
B) 6 years
C) 9 years
D) 12 years
E) 15 years
C) 9 years
Which microorganism is the leading cause of serious infection in HIV infected children?
A) Cryptococcus neoformans
B) Mycobacterium tuberculosis
C) Pneumocystis jirovecii
D) Toxoplasma gondii
E) Yersinia enterocolitica
C) Pneumocystis jirovecii
HBsAg positive mother gave birth to a term baby, birthweight is 3.3 kg. Following a careful wash of the baby which vaccination order would you apply from the list below?
A) Hepatitis B immunoglobulin (HBIG) and HBV vaccine at birth, 1 month and 6 month of age
B) HBV vaccine at 2, 4, 6 and 18 month of age
C) HBIG at birth, 1 and 6 month of age
D) HBIG and HBV vaccine at 2,4,6 and 18 month of age
E) HBIG at birth and 1 month of age and HBV vaccine at 2,4,6 and 18 month of age
A) Hepatitis B immunoglobulin (HBIG) and HBV vaccine at birth, 1 month and 6 month of age
There is a contagion in a nursery school. Children showing symptoms of upper airway infections, bronchitis, pneumonia, conjunctivitis and watery diarrhoea. Which virus is the most likely causative agent from the list below?
A) adenovirus
B) enterovirus
C) herpesvirus
D) parvovirus
E) rhinovirus
A) adenovirus
A one year old infant has a three days history of fever of 39.4°C which is difficult to relieve. During the physical examination the baby is noted to have a maculo-papular, blanching rash on his trunk but his upper extremities, the face and the lower extremities are spared. At the time of attendance the infant is afebrile. Which virus is the most probably infective agent in this case?
A) Adenovirus
B) Enterovirus
C) Human herpesvirus 6/7
D) Parvovirus B19
E) Rubella-virus
C) Human herpesvirus 6/7
One of the following statements is true in reference to toxoplasmosis:
A) pregnant women are treated with pyrimethamine and sulfadiazine if they had tainted with toxoplasma before conception
B) in case of congenital toxoplasmosis confirmed with serology test infants are treated with pyrimethamine and sulfadiazine
C) to prevent congenital toxoplasmosis pregnant women should be treated with spiramycin during the first trimester
D) lymphadenopathy due to toxoplasma infection should be treated with spiramycin
E) in case of ocular toxoplasmosis systemic steroid therapy is sufficient
C) to prevent congenital toxoplasmosis pregnant women should be treated with spiramycin during the first trimester