Infectious Disease Treatments Flashcards
Bacterial Vaginosis
- oral metronidazole
- alt: topical metronidazole or topical clindamycin
Bacterial Vaginosis with Pregnancy
-oral metronidazole throughout pregnancy
Chlamydia
- doxycycline
- alt: azithromycin
Chlamydia in Pregnancy
- azithromycin
- erythromycin
- amoxicillin
Lymphogranuloma Venereum
Doxycycline
Gingivostomatitis in Herpes
- oral aciclovir
- chlorhexidine mouthwash
Cold sores in Herpes
-topical aciclovir
Genital Herpes
- oral aciclovir
- saline bathing
- topical anaesthetic e.g. lidocaine
- analgesia
Genital Warts
- multiple, non-keratinised: topical podophyllum
- single, keratinised: cryotherapy
- 2nd line: topical imiquimod
Gonorrhoea
- ciprofloxacin
- now more common IM ceftriaxone (+ oral azithromycin)
- alt: oral cefixime + oral azithromycin
Non-gonococcal Urethritis
azithromycin or doxycycline
Syphilis
- IM benzathine penicillin
- doxycycline
Trichomonas Vaginalis
oral metronidazole 5-7 days
Urethritis
- 7 days doxycycline
- 1 dose azithromycin oral
Lower UTI in non-pregnant women
- trimethoprim/nitrofurantoin
- culture if >65 yo or haematuria or pregnant
Lower UTI in pregnant women
-nitrofurantoin (avoid near term), amoxicillin or cefalexin
Lower UTI in catheterised patients
- no treatment if asymptomatic
- symptomatic, Abx 7 days
Acute pyelonephritis
broad spec cephalosporin or quinolone 10-14 days
Amoebiasis Tx
metronidazole
luminal amoebicide for cystic stage
Animal and human bites
co-amoxiclav
doxycycline and metronidazole
Anthrax
ciprofloxacin
Botulism
botulism antitoxin (only effective early on)
Campylobacter
clarithromycin
ciprofloxacin
Cellulitis
flucloxacillin
allergic: clarithromycin, erithromycin (pregnancy), doxycycline
severe: co-amoxiclav, cefuroxime, clindamycin, ceftriaxone
Cholera
doxycycline, ciprofloxacin
Diphtheria
IM penicillin
diphtheria antitoxin
Giardiasis
metronidazole
Legionella
clarithromycin/erythromycin
Leprosy
- rifampicin
- dapsone
- clofazimine
Leptospirosis
benzylpenicillin, doxycyline
Lyme disease
- doxycyline
- ceftriaxone
Malaria
- artemisin based combination therapies
- chloroquine
- ovale/vivax - primaquine after acute treatment
Meningitis
- cefotaxime
- add amoxicillin if <3mo or >50 yo
- meningococcal: or benzylpenicillin
- listeria: amoxicillin and gentamicin
- or chloramphenicol if CONTRA
- IV dexamethasone reduces risk neurological sequelae
- prophylaxis for contacts: oral ciprofloxacin or rifampicin
MRSA
vancomycin, teicoplanin, linezolid
Mycoplasma Pneumoniae
doxycycline or macrolide (erythromycin/clarithromycin)
Strongyloides Stercoralis
ivermectin and albendazole
Tetanus
metronidazole (vaccination)
Toxoplasmosis
pyrimethamine and sulphadiazine
no treatment if immunocompetent
Trypasonomiasis
Benznidazole or nifurtimox
Tuberculosis
rifampicin, isoniazid, pyrazinamide, ethambutol
What are the serology treatments like post syphilis treatment?
TPHA positive
VDRL negative
Erysipelas:
flucloxacillin
When should trimethoprim and nitrofurantoin be avoided in pregnancy?
- trimethoprim throughout
- nitrofurantoin avoid near term
