Infectious Disease II (lab) - no worms

Question 1

Describe Koplik spots and the diagnosis.

Answer 1

These are white spots on oral mucosa and are pathopneumonic for Measles

Question 2

Teenage boy with bilateral parotitis and orchitis. Dx?

Answer 2

Mumps

Question 3

Flask shaped ulcer in the cecum or ascending colon after a visit to Mexico. What is the likely causal organism?

Answer 3

Entamoeba histolytica

Question 4

Sexually active women who reported a “sore” on her vulva that healed a couple of weeks ago. She now has a rash on her palms and soles. What is the cause and possible cardiac complication that may result if not treated?

Answer 4

Syphilis is caused by T. palladum and can cause aortic dilation.

Question 5

After antibiotic treatment someone is shitting their pants. What is the mechanism by which tissue is being damaged?

Answer 5

This is C. difficile. Its enterotoxin (TcdA) results in an inability to synthesize proteins.

Question 6

Kid with exposure to ticks comes in with fever, headache, and extensive rash. What is the pathophysiology of the disease?

Answer 6

Rocky Mountain Spotted Fever (rickettsia rickettsii) infects endothelial cells causing perivascular inflammation.

Question 7

How can one differentiate between malaria and Babesia?

Answer 7

Babesia have a tetramer shape in RBCs.

Malaria shows the ring form