Infectious Disease and Immunizations Flashcards
- Which immunity is considered long-lasting?
- Which immunity provide temporary protection that wanes with time?
- Active
- Passive
Which immunity is transferred from another human or animal?
Passive or active
Passive
Which type of immunity is due to natural infection or vaccination?
Passive or Active
Active
Why is immune globulin given?
which type of immunity does this fall under?
given to children that cannot get vaccines due to being immunocomprosed
Passive
What are the guidelines for administring multiple live vaccines?
- Must be given at the same time
- **or 28 days apart **from each other
What are the three classifications of vaccines?
- Live attenuated
- Inactivated
- Recombinant vaccines
Which classification of vaccine requires multiple doses?
Inactivated
Which classification of vaccine is produced by genetic engineering?
What are two examples of?
Recombinant vaccines
HPV and Heb B
Which vaccine classification usually only requires one dose and a modification of a disease producing virus or bacteria?
Live attenuated
Which classification of vaccine contains a weakened virus/bacteria that retains its ability to replicate?
Live attenuated
What type of general contraindication is given for vaccines that cause a moderate or severe acute illness w/ or w/o fever?
Precaution
What type of general contraindication is given for all vaccines that cause a severe allergic reaction (e.g., anaphylaxis)?
Permanent
True or False
There are no specific contraindications for certain vaccines
False
a set of rules and procedures that ensure the proper storage and distribution of vaccines is referred to as?
Cold chain
What six things should you document when administering a vaccine?
- Vaccine manufacturer
- Lot number
- Injection site
- Date of administration
- Vaccine Information Statement
- Name & Title of person administrating vaccine
- What is the first vaccine given to children?
- When is it given by?
- Heb B
- Within 2 weeks of birth
Which age do you follow to vaccinate premature infants?
Preterm infants should receive the full dose at the appropriate chronologic age.
The age from his actual birth is his chronological age
True or False
Vaccines in a series cannot be given sooner than indicated.
True
What is the mercury-containing compound found in trace amounts in some vaccines?
misconceived to be a link to autism
Thimerosal
When should vaccines be drawn into syringes?
Immediately prior to administration
Name three (non-pharmalogical) pain control methods for pediatrics
- Distraction
- Child on parent’s lap
- Ice to numb
True or False
Vaccines can be mixed in the same syringe unless contraindicated by the FDA
False
FDA informs which vaccines can be mixed together; not contraindicated
What angle should IM injection be given at?
90
What angle should SubQ be injected at?
45
Which area is recommened for IM injection in infants < 1?
anterolateral thigh muscle
Which area is recommended for IM injection in children (> 1) ?
Thickest portion of deltoid
avoid the acromion processs
Where is the injection site for SubQ after 1 year of age?
Tricep
- The nurse should pinch up the skin for what type of injection?
- Which injection is spreading of the skin indicated?
- SubQ
- IM
Which stage of infectious disease is characterized by vague (non-specfic) symptoms?
Prodromal
(Catarrhal)
Which stage of infectious disease is the disease most contagious to others?
Prodromal
(Catarrhal)
commonly URI (rhinorrhea, sneezing, cough), low grade fever,
Which stage of infectious disease are the S&S most severe and distinct symptoms appear?
Constitutional (Paroxysmal) stage
What type of precaution would pertussis whooping cough be?
Contact, Droplet, and indirect contact w/ contaminated objects
What are the two permanent contraindications for DTap?
- Allergic reactions (Anaphylaxis)
- Brain of nervous system disease (seizures occur within 7 days)
What vaccine is given preventively for pertussis?
DTap
Diphtheria, Tetanus, and Pertussis
What should expectant mothers be notified regarding DTap?
should receive DTap during each pregnancy
preferably at 27 through 36 weeks.
How is Pertussis Whooping Cough diagnosed?
Nasopharyngeal swab or aspirate
PCR test
- What is the greatest complication with pertussis whooping cough?
- Which stage would it occur during?
- Pneumonia
- Stage 3 Convalescent Stage (2-3 weeks)
What is responsible for causing shingles later in life?
Varicella remaining latent in dorsal root ganglia
How is varicella spread?
chicken pox
- Direct contact
- Droplet
- Contact w/ contaminated objects
When does a person with varicella begin and stop being contagious?
chicken pox
- 1-2 days before rash
- Contagion ceases when all lesions have crusted over
incubation period of varicella zoster is about 2-3 weeks
How is varicella diagnosed?
- Physical assessment
- PCR
What medication is contraindicated during varicella?
Why?
Aspirin
Risk for Reye’s syndrome
What are the complications with varicella?
Secondary infections via lesions/skin
When is the varicella vaccine permanently contraindicated?
Life threatening reactions to:
1. previous varicella vaccine
2. Gelatin
3. Neomycin
Not including rash, hives, etc
When are live vaccines temporarily contraindicated?
- Pregnant women*
- Immunocompromised (HIV, Cancer treatment)
- Steroid regimen (wait 3 months)
- Blood transfusion (wait 3 months)
*month before pregnancy and month after confirmation of pregnancy
Which two patient populations need to be monitored closely when exposed to fifth disease?
(Erythema Infectious)
- Pregnant women*
- Patients w/ sickle cell anemia
*risk for fetal demise
How is fifth’s disease transmitted?
- Respiratory secretions
- Blood
What are Kernig’s and Brudzinski’s signs used to assess for?
Bacterial Meningitis
What is a positive Kernig’s sign?
Knee Extension pain
KErnig sig
What is a positive Brudzinski sign
Neck Flexion causes Knee Flexion
Which pathogen causes the most severe form of meningitis?
Neisseria meningitidis
Which the of the following causes meningitis in newborns?
- Streptococcus pneumoniae
- Neisseria meningitidis
- Haemophilus influenzae
- Streptococcus Group B
- Listeria Monocytogenes
- E. Coli
- Strep Group B
- E. Coli
- Listeria Monocytogenes
Which the of the following causes meningitis in infants/children?
- Streptococcus pneumoniae
- Neisseria meningitidis
- Haemophilus influenzae
- Streptococcus Group B
- Listeria Monocytogenes
- E. Coli
- Strep Group B
- Streptococcus pneumoniae
- Neisseria meningitidis
- Haemophilus influenzae
Which the of the following causes meningitis in Adolescents ?
- Streptococcus pneumoniae
- Neisseria meningitidis
- Haemophilus influenzae
- Streptococcus Group B
- Listeria Monocytogenes
- E. Coli
- Streptococcus pneumoniae
- Neisseria meningitidis
Which the of the following DO NOT causes meningitis in Older adults
- Streptococcus pneumoniae
- Neisseria meningitidis
- Haemophilus influenzae
- Streptococcus Group B
- Listeria Monocytogenes
- E. Coli
E. Coli
How is bacterial meningitis diagnosed?
- Blood cultures
- Cerebral spinal fluid via spinal tap
Which of the following do not have vaccines
- Pertussis whooping cough
- Varicella
- Fifth Disease
- Measles (rubeola)
- Infectious mononucleosis (epstein-barr)
- Bacterial meningitis
- Fifth disease
- Infectious mononucleosis
What are the three live vaccines discussed?
- Varicella
- MMR
- Rotavirus
Which two vaccines have a permanent contraindication for yeast allergy?
- Hep B
- HPV*
Human Papillomavirus
acronym for what?
VAERS
Vaccine Adverse Event Reporting System
(VAERS)
co-sponsored by the CDC and FDA
What can hepatitis B cause if unvaccinated?
Cirrhosis* or liver cancer
Chronic liver damage leading to scarring and liver failure.
Which vaccine prevents you from donating blood for 28 days?
Hep B vaccine
(may test positive for HBsAg and become permanently disqualified as blood donors.)
Which vaccine should be given to by 18 years of age
Hep B vaccine
- Which vaccine is given orally?
- How many doses are given?
- Rotavirus vaccine
- two-three doses depending on brand
(1st dose: 2 mo/ 2nd dose 4 mo/ 3rd dose 6 mo)
Which vaccine is permanetly contraindicated if allergy to latex, previous case of intussusception, or immunosuppressant?
Rotavirus vaccine
Additionally: other live vaccine contraindications
What is the most common STD?
sexually transmitted disease
Human Papillomavirus (HPV)
What can cause cervical, oral, vaginal, anal, and penile cancer?
Human Papillomavirus (HPV)
- Brief fainting spells and jerking movements has been associated w/ which vaccine?
- What is the recommendation for this?
- HPV vaccine
- Wait in the office for 15 mins after administration
Human Papillomavirus
What are the recommended ages for the HPV vaccine?
Human Papillomavirus
- Famales through 26
- Men through 21
What is the only approved HPV vaccine in the U.S.?
Gardasil 9
What are the three vaccines contraindicated during pregnancy?
- MMR
- Varicella
- HPV
Which age is approved for Flu shot?
People older than 6 months
How does varicella rash change over time?
Centripetal (starts at chest then outward)
Macular (flat) → papular (red bumps) → vesicular (fluid filled) → crusting
What are the 3 stages of rash for Fifths Disease (Ertyhema Infectiosum)
- “Slapped cheeks”
- 1 day later, “lacy” maculopapular rash on extremities
- Rash subsides*
Polyarthropathy Syndrome (joint pain) starts
Which disease is caused by parvovirus B19?
Fifth Disease (Erythema Infectious)
Koplik spots are associated w/ which disease?
small, white spots on the mouth
Measles (Rubeola)
What is the triad of mono?
3 most common symptoms of mono along w/ exhaustion
- Sore throat
- Fever
- General lymphadenopathy*
*Swollen lymph nodes
How is infectious mononucleosis transmitted?
- Oral secretions
- Blood transfusion/transplantation
Mengingitis photophobia is a clinical manifestation in infants or children/adolescence?
eye discomfort in bright lights
Children and Adolescents
The nurse knows which signs or symptoms of measels (rubeola) are exhibited before the appearance of the rash?
- Coryza (common cold)
- Cough
- Conjunctivitis
Rmb: 3 C’s of Measles (Rubeola)