Infectious disease: Aids

Question 0

< 50 T cell

Answer 0

Prophylaxis for mycobacterium avium complex

Azithromycin 1 per week

Question 1

< 200 T cells

Answer 1

Prophylaxis for pneumocystis with trimethoprim sulfamethoxazole

If allergic go to dapsone or atovaquone

Question 2

Toxoplasmosis prophylaxis

Answer 2

Already on trimethoprim sulfa

Question 3

Anemia

Answer 3

Zidovudine

Question 4

Hyperglycemia hyperlipidemia

Answer 4

Protease inhibitors

Question 5

Peripheral neuropathy

Answer 5

Stavudine and didanocine

Question 6

Flank pain and hematuria

Answer 6

Indinovir

Question 7

Limivudine

Answer 7

No adverse effect

Also good with hepatitis b

Question 8

Typical drug regime

Answer 8

2 nucleocide reverse transcriptase inhibitors (azt, didanocine, Stavudine )

1 protease inhibitor or efavrins

No efavrins in pregnancy

Question 9

High viral load in pregnancy

Answer 9

> 1000

Question 10

When do start antiretrovirals?

Answer 10

< 350 T cells or high viral load

Question 11

If pregnant patient with high T cell count or low viral load

Answer 11

Only give antiretrovirals during the second and third trimester to prevent transmission

Question 12

High viral load

Answer 12

50000- 100000

Except pregnancy in which 1000 is high requiring c-section

Question 13

Post exposure prophylaxis

Answer 13

2 nucleocide reverse transcriptase inhibitors and protease inhibitor or efavrins for 1 month

Question 14

Kaposi sarcoma

Answer 14

Human herpes virus 8

Under 200 tcells

Question 15

Pneumocystis

Answer 15

Bactrim

Add steroids if severe

Question 16

Toxoplasmosis

Answer 16

Ring enhancing lesion in brain

Diagnosis by treating with Bactrim and see if lesions go away

Question 17

Cytomegalovirus

Answer 17

Unusual

Retinitis < 50 T cells and blurry vision

Gangcyclovir (anemia) or phoscarnate (renal toxic)

Question 18

Immune reconstitution

Answer 18

Can develop infections after starting antiretrovirals. Unknown reason.