Infectious Disease Flashcards
White, curd-like vaginal discharge should make you think of what diagnosis?
Vulvovaginitis (Vaginal candida infection)
Owl eye inclusion bodies should make you think of what diagnosis?
Cytomegalovirus (CMV)
If you have a patient with positive blood cultures for candida what is the first line drug?
Amphotericin B
What is the treatment for pertussis?
Erythromycin for 7 days
What disease does Rickettsia ricketsii cause?
Rocky mountain spotted fever
An india ink stain showing cysts should make you think of what diagnosis?
Cryptococcosis
A COPD patient has apical cavities and clarified nodes on his chest x-ray. You also discover that he has a pet bat and a few birds. What diagnosis should you be thinking of?
Histoplasmosis
An HIV patient presents with nonproductive cough and a chest x-ray showing diffuse interstitial infiltrates. What diagnosis should you be thinking of?
Pneumocystitis jiroveci pneumonia (PCJ)
Honey and babies should make you think of what diagnosis?
Botulism
What type of organism causes botulism?
A gram + rod, clostridium botulinum
What is the treatment for botulism?
Antitoxin
A patient presents to the ER with acute progressive weakness, diplopia and a very dry mouth. What organism may be causing this?
Clostridium botulinum
Rice water stool should make you think of what diagnosis?
Cholera
Is diphtheria a gram positive or negative organism?
Gram positive
A stuck on grey membrane in the pharynx should make you think of what diagnosis?
Diptheria
What are the four steps in treating diphtheria?
Antitoxin, PCN, remove membrane and report the case to the CDC
What type of organism is tetanus?
A gram + rod, Clostridum tetani
A patient ate out last night and today has cramping and bloody diarrhea. What is the most likely organism?
Salmonella
Diarrhea with blood and mucus should make you think of what diagnosis?
Shigella
What ist he best test to diagnose malaria?
Peripheral blood smear
What organism has been linked to reactive arthritis?
Shigella
What is the treatment for shigella?
Bactrim or FQs and hydration
What organism causes lyme disease?
Borrelia burgdoferi
What is the minimum amount of time needed for a tick to transfer lyme disease?
24 hours
What is the drug of choice to treat lyme disease in kids or pregnant women?
Amoxicillin
What is the drug of choice to treat c. diff?
Metronidazole (flagyl)
A patient was in the woods yesterday and today presents with erythema migrans. What diagnosis should you be thinking of?
lyme disease
What drug is used for the treatment or prophylaxis of malaria?
Chloroquine
A patient went camping a few days ago and now has a rash tag began on his wrists and ankles. What diagnosis should you be thinking of?
Rocky mountain spotted fever
What is the drug of choice in rocky mountain spotted fever?
Doxycycline
What is the drug of choice for the treatment of syphillis?
PCN
Any reference to the dark field microscopy should make you think of what organism?
Treponema pallidum
Is staph a gram positive or negative organism?
Gram +
A patient is being treated with PCN for a syphillis infection develop fever, chills, muscle pains, and headaches. Do you stop treatment?
No this is Jarisch-Herxheimer reaction. The patient must be closely monitored, but it is a response to released endotoxin from the death of the spirochetes and is not an allergic reaction
A painless, clean base chancre should make you think of what diagnosis?
Primary syphillis
A patient complains of a rash on his palms and soles. He has a fever and chills. In conversation he mentions a strange painless chancre he had a few weeks ago. What diagnosis should you be thinking of?
Secondary syphillis, this is the most painless stage.
What is the treatment for cholera?
Fluids
What ist he current drug of choice for the cytomegalovirus?
Ganciclovir
Which herpes virus causes EBV?
Herpes 4
A 16 year old girl presents with an exudative sore throat and general malaise. On physical exam you observe come posterior chain lymphadenopathy and mild splenomegaly. What diagnosis should you be thinking of?
EBV
What are the two most important pieces of patient education for anyone diagnosed with mononucleosis?
No contact sports - high risk of splenic rupture
No kissing! Highly contagious
What is the fist symptom of a rabies infection?
Pain and anesthesia at the site of the bite
What is the best way to be sure a patient has rabies?
Pathology of the brain of the animal that performed the bite using fluorescent antibody stain
A patient is bitted by an infected raccoon. On what days do you give human diploid cells?
0, 3, 7, 14, 28
A diaper rash with satellite lesions should make you think of what diagnosis?
Candida
What are two side effects of vancomycin?
Nephrotoxicity and ototoxicity
What is the DOC for the treatment of lyme disease?
Doxycycline
What does trismus mean?
Lock jaw, often secondary to tetanus
How do you treat amebiasis?
Metronidazole
How do you treat pneumocycistis jiroveci pneumonia?
Bactrim
What is the treatment for a tetanus infections?
PCN, immune globulin and supportive care esp. respiratory support
How do hookworm larvae enter the body?
They penetrate the skin usually through the soles of the feet
How do you treat hookworm?
Azoles
What type of mosquitoes carry malaria?
Anopheles
How do you treat white oral plaques that can be scraped off?
The most likely is candida. Topical nystatin or oral fluconazole 1mg are the first line choices.
A CT scan shows ring enhancing lesions in an HIV patient. What diagnosis should you be thinking of?
Toxoplasmosis
What is the drug of choice for toxoplasmosis?
Bactrim
What organism causes toxoplasmosis?
Toxoplasma gondii
What drug do you use to treat pinworm?
You treat everyone in the house with albendazole. Two weeks later treat them again.
The scotch tape test is used to diagnose what kind of disease?
Pinworm
Is neisseria gram + or gram -
Gram -
Syphillis is caused by what organism?
Treponema pallidum
A gram + organism in chains should make you think of what diagnosis?
Strep
A negative diplococci should make you think of what diagnosis?
Neisseri
What is the most common prophylactic antibiotic used preoperatively?
Cephalexin
What is the suffix for most fluoroquinolone?
Oxacin
Why aren’t fluoroquinolone used more frequently?
Many side effects
A patient presents with a ruptured achilles tendon. He states that he was recently in the hospital for a “blood infection and on a ton of antibiotics” What antibiotic class might he have been on?
Fluoroquinolones
Why can’t you give fluoroquinolone to kids?
They can cause cartilage development problems
What class of antibiotics should you start with for community acquired pneumonia?
Macrolides
What class of antibiotics is sometimes prescribed specifically for its effects on increasing GI motility?
Macrolides
Which medication is worse to give to a pediatric patient, tetracycline or amino glycoside?
Tetracycline
Pizza pie retinopathy should make you think of what diagnosis?
Cytomegalovirus
A patient presents complaining of metallic taste in her mouth and dark brown urine. What antibiotic might she be on?
Metronidazole
What antibiotic is the most common cause of C. diff?
Clindamycin
What is the current drug of choice for treating MRSA?
Vancomycin
You place a patient on Rifampin. What side effect should you warn her about?
Orange-red discoloration of body fluids.
What happens if you infuse vancomycin too fast?
Red man syndrome
Name one medication that can be used for MRSA
Linezolid
What organism is most commonly responsible for community acquired pneumonia?
Strep pneumoniae
What organism is the most common cause of an uncomplicated UTI?
E. Coli
Gummas or granulomatous nodules should make you think of what diagnosis?
Tertiary syphillis
Bloody stool with cysts and trophozoites should make you think of what diagnosis?
Amebiasis
Community acquired carditis is most often caused by once of the HACEK organisms. What are the HACEK organisms?
Haemophilus Actinobacillus Cardiobacterium Eikenella Kingella
What are the three medications often combined as a first line treatment for H. pylori?
Omeprazole, clarithromycin, and amoxicillin (PPI and 2 abx)
What is the prophylactic antibiotic most commonly given before a dental procedure if one is necessary?
Amoxicillin 2 grams po 1 hour before procedure
Pregnant women and cat litter should make you think of what diagnosis?
Toxoplasmosis
What is the DOC to treat urethritis caused by neisseria?
Ceftriaxone
Is klebsiella gram + or gram -
Gram -
A gram positive organism in clusters should make you think of what diagnosis?
Staph
What is the best test for diagnosing rocky mountain spotted fever?
Indirect immunofluorescent antibodies
A gram - coccobacilli found in the sputum of a patient with pneumonia should make you think of what diagnosis?
H. flu
What medication is used as prophylaxis for meningococcal meningitis?
Rifampin