Infectious Disease Flashcards
Which type of viral hepatitis should travelers be vaccinated against?
A
Who is at greatest risk for fulminant Hep E?
Pregnant women
Hat is the most common cause for liver transplant in the U.S.?
Hep C
How do you define chronic HBV?
Surface Ag for >6 mos.
What HBV antigen is in the vaccine?
Surface Ag
What is the Tx of chronic HCV?
Interferon and ribavirin
What is the most common side effect of interferon therapy?
Flu-like symptoms
What is the most common side effect of Ribavirin?
Red cell anemia
What are the two older drugs for chronic HBV?
Interferon OR lamivudine
What are the two newest treatments for chronic HBV?
Entecavir OR adefovir
Are the HBV drugs more effective against e Ag positive or negative disease?
HBeAg positive (block DNA polymerase the most)
What is HBeAg?
DNA pol