Infectious Disease Flashcards

1
Q

Epiglottitis organism

A

H.Influenzae

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2
Q

Symptoms of infectious mononucleosis
What abx canuses problems

A

URTI symptoms + amoxicillin -> rash ?glandular fever

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3
Q

Symptoms of Kawasaki Disease and at what age group?

A

Age 5 and under
Fever for 5 days at least, conjuctival injection rash, cervical lymphadenopathy

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4
Q

Features of infectious mononucleosis

A
  • malaise, anorexia,headache
  • palatal petechiae
  • URTI
  • Hepatitis
  • Splenomegaly
  • Lymphocytosis
  • Haemolytic anaemia secondary to cold agglutins IfM
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5
Q

PCP complication

A

Pneumothorax
- PCP causes cystic changes in lungs -> more prone to collapse

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6
Q

In HIV patients with PCP, sudden dyspnea + pleuritic pain

A

Think pneumothorax!

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7
Q

Prophylactic meningitis N.Meningitidis abx

A

Ciprofloxacin / Rifampicin

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8
Q

Renal transplant + infection

A

?CMV

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9
Q

What is Valency?

A

valency refers to how many different types or strains of a virus or bacteria a vaccine protects against

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10
Q

Pruritic rash on the buttocks or soles - Trip to brazil

A

Strongyloides Stercoralis

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11
Q

Haematuria and fevers + freshwater exposure

A

Schistosomiasis

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12
Q

Tx for Schistcosomiasis

A

Ivermectin and Albendazole

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13
Q

Test for infective mononucleosis

A

Heterophile antibodies (monospot)

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14
Q

Diptheria common sign

A

severe pharyngitis
“dip in the throat”

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15
Q

Staining for PCP

A

Silver stain

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16
Q

Which NRTI causes renal toxicity & osteoporosis?

17
Q

Which NRTI causes anaemia and black nails?

A

Zidovudine

18
Q

Which NRTI causes pancreatitis?

A

Didanosine

19
Q

Which NNRTI causes vivid dreams and CNS effects?

20
Q

Which NNRTI is a P450 inducer and can cause a rash?

A

Nevirapine

21
Q

Which PI causes kidney stones?

22
Q

Which PI is a strong P450 inhibitor and is used to boost other PIs?

23
Q

Which class of ART causes lipodystrophy, diabetes, and hyperlipidaemia?

A

Protease inhibitors (PUFFERS)

24
Q

What is the mechanism of integrase inhibitors?

A

They block the integration of HIV DNA into the host genome

25
What are the classic constitutional symptoms of TB?
Fever, weight loss, night sweats
26
What is the most common organ affected by TB?
Lungs (Pulmonary TB)
27
How does TB cause hypoadrenalism?
Haematogenous spread → progressive adrenal destruction
28
What are common signs of TB meningitis?
Indolent onset, cranial nerve palsies (optic & abducens nerves), headache, fever
29
What skin condition is associated with TB?
Erythema nodosum
30
What causes peripheral neuropathy in TB patients?
Isoniazid & Linezolid (TB medications)
31