Infectious Disease Flashcards
botulism is a gram _ bacteria
positive
presentation of botulism
respiratory paralysis
muscle weakness
floppy baby
in order to destroy botulism spores, they must be exposed to
moist heat at 120 C x 30 mins
when can you expose a kiddo to honey
12 months old
due to risk of botulism
tx for botulism
botulinum antitoxin
4 different types of candidial infxns to know
vaginal
esophageal
oral thrush
intertrigo
tx for vaginal candidiasis
miconazole cream
PO fluconazole
esophageal candidiasis is mc in _ pt’s
AIDS
sx of esophageal candidiasis
substernal dysphagia
GE reflux
nausea w/w.o pain
what is this showing
linear erosions on EGD -> esophageal candidiasis
tx for esophageal candidiasis
fluconazole
friable white plaques that bleed if scraped
oral thrush
tx for oral thrush
nystatin
what is this showing
intergrigo
hallmark rash of intertrigo
beefy red erythema w. distinct scallped borders and satellite lesions
tx for intertrigo
clotrimazole
ketoconazole
miconazole
mc STI:
most reported STI:
mc: HPV
most reported: chlamydia
describe chlamydia bacterium
gram negative rod
dx for chlamydia
NAAT
gram stain shows no organisms
tx for chlamydia
doxycycline
+
ceftriaxone (cover for gonorrhea)
tx for chlamydia in pregnancy
azithromycin
vs
amoxicillin
describe the vibrio cholerae bacterium
gram negative
hallmark sx of cholera
rice water diarrhea
2 mc modes of transmission for cholera
contaminated water
seafood
gs dx for cholera
stool culture
tx for cholera
aggressive rehydration
macrolides vs FQ vs tetracyclines
cryptococcus is a _ defining illness
AIDS
dx for cryptococcus (2)
CSF - india ink
serology
transmission of cryptococcus
inhalation of budding yeast from contaminated soil w. pigeon/bird droppings
tx for cryptococcus
ampho B + flucytosine
followed by
fluconazole
cryptococcus prophylaxis for HIV pt
fluconazole if CD4 < 100
enveloped double stranded linear DNA virus in the herpes family - aka herpesvirus 5
CMV
CMV may mimic _
but lacks what sx
EBV
lacks: severe pharyngitis
what is this showing
CMV retinitis
3 s/sx of CMV
PNA
retinitis
esophagitis (immunocompromised)
CMV is associated w. a CD4 count <
50
3 sx of CMV in neonates
hearing loss
sz
petechial rash
what is this showing
owl’s eye inclusion -> CMV
tx for CMV
ganciclovir
foscarnet
cidofovir
URI w. thick gray pseudomembrane in the throat that bleeds if scraped
diphtheria
what is this showing
gray pseudomembrane of diphtheria
what is this showing
bull neck swelling due to enlarged cervical LAD -> diphtheria
vaccination schedule for diphtheria
2, 4, 6, 15-18 mos
booster 4-6 yo
tx for diphtheria
antitoxin
pcn vs macrolide
EBV triad
fever
LAD
pharyngitis
dx for EBV
(+) heterophile abs screen
atypical lymphocytes w. enlarged nuclei
_ develops in 80% of pt’s w. EBV
maculopapular rash
athletes w. EBV should avoid contact sports for _ weeks
3-4
describe the gonorrhea bacterium
gram negative diplococcus
gonorrhea in women is often asymptomatic, what are some sx of gonorrhea in men
yellow, creamy, profuse, purulent urethral d.c
tx for gonorrhea
ceftriaxone
+
azithro vs doxy (tx for chlamydia)
4 complications of gonorrhea
neonatal conjunctivitis
septic arthritis
tenosynovitis
hand/feet pustules
2 hallmark sx of HSV infxns
prodrome burning/tingling > 24 hr
followed by
painful grouped vesicles on an erythematous base
name the HSV viruses type 1-8
HSV 1: oral HSV
HSV 2: genital herpes
HHV 3: varicella zoster: chickenpox, shingles
HHV 4: EBV, hodgkin lymphoma
HHV 5: CMV
HHV 6/7: roseola infantum
HHV 8: kaposi sarcoma
histoplasmosis is a _ defining illness
histoplasmosis
transmission of histoplasmosis
soil containing bird/bat droppings in the mississippi and ohio river valleys
most significant rf for histoplasmosis
CD4 < 100
lab findings of histoplasmosis
elevated ALP
(+) LDH
tx for histoplasmosis
- itraconazole
- ampho B
t/f: histoplasmosis prophylaxis for AIDS pt’s is recommended
f
dz’s associated with CD4 counts
-500-200: TB, kaposi sarcoma, thrush, lymhoma, zoster
-<200: PJP, histoplasmosis
-<100: toxoplasmosis, cryptococcus
-<50: MAC, CMV
prophylaxis for different CD4 levels
-500-200: isoniazide
-<200: bactrim, itraconazole
-<100: bactrim, fluconazole
-<50: valganciclovir
PEP administration guidelines
-w.in 72 hr of exposure
-chances of contracting HIV from needle stick injury in knwon HIV pt is <0.3%
-test worker and pt at 6 weeks, 3 mos, 6 mos
-if retrovirals: combo therapy w. drugs from 2 different classes x 4 weeks
full PEP reduces HIV transmission by up to _%
70%
influenza is caused by the _ virus
orthomyxo
everyone >/= _ yo should receive the influenza vaccination
6 mos
contraindications to the influenza vaccination
severe egg allergy
previous rxn
guillain barre hx w.in 6 weeks of prev vaccination
GBS in past 6 weeks
< 6 mos old
contraindication to flumist flu vaccine
asthma
CXR findings of influenza pna
bilat diffuse infiltrates
which 2 antivirals tx influenza a and b
oseltamivir
zanamivir