Cardiovascular Flashcards
predictable chest pain relieved by rest and/or nitro
stable angina
previously stable/predictable chest pain that is more frequent, increasing, or present at rest
unstable angina
coronary artery vasospasm that causes transient ST segment elevations NOT associated w. ischemia/clot
primzmetal variant angina
cardiac arrhythmias/conduction d.o’s to know
premature beats
paroxysmal SVT
afib/flutter
sick sinus syndrome
sinus arrhythmia
ventricular arrhythmias to know
pvc’s
v tach
v fib
torsades
what are the 3 types of premature beats
pvc
pac
pjc
what is this showing
early wide, bizarre qrs
no p wave
pvc
what is this showing
abnormally shaped p wave/qrs
pac
what is this showing
narrow qrs
no p wave or inverted p wave
pjc
what is this showing
narrow, complex tachy
no discernable p wave
svt
what is this showing
irregularly irregular rhythm
disorganized/irregular atrial activity
absence of p waves
afib
what is this showing
regular, sawtooth pattern
narrow qrs
aflutter
what is this showing
alternating brady-tachy
sinus arrest
prolonged absence of sinus node activity - absent p waves > 3 seconds
sick sinus syndrome
normal/minimal variations in SA node pacing rate associated w. phases of respiration (increase w. inspiration, decrease w. expiration)
sinus arrhythmia
what is this showing
3 or more consecutive pvc’s
broad qrs tachy
v tach
what is this showing
erratic rhythm
no discernable waves
vfib
what is this showing
polymorphic v tach twisting around a baseline
torsades
3 cardiomyopathies to know
dilated
hypertrophic obstructive (hocm)
restrictive
mc cardiomyopathy
dilated
event or pathologic process damages the myocardium -> weakens heart muscle -> decreased ventricular contraction/strength -> dilated left ventricle
dilated cardiomyopathy
dilated cardiomyopathy causes _ heart failure
systolic
3 causes of dilated cardiomyopathy
CAD
MI
arrhythmia
4 PE findings of dilated cardiomyopathy
dyspnea
S3 gallop
rales
JVD
which abnl heart sound can be a normal finding in kids, pregnant females, and well trained athletes
S3
which extra heart sound is always pathologic
S4
tx for dilated cardiomyopathy
no etoh
ACEI
diuretic
genetic mutation -> hypertrophic portion of ventricular septum -> thickened cardiac muscle -> narrowed LV outflow tract
HOCM
3 HPI clues for HOCM
young athlete
positive fam hx of sudden death
syncopal episode
HOCM causes _ heart failure
diastolic
3 PE findings of HOCM
sustained PMI
S4 gallop
mid systolic murmur
describe the HOCM murmur (3)
high pitched
midsystolic
heard best at LLSB
the HOCM murmur is increased with _ (2)
and decreased w. _
increased: standing, valsalva
decreased: squatting, handgrip
management of HOCM (4)
refrain from PA
bb vs ccb
surgery vs ablation
defibrillator insertion
6 causes of restrictive cardiomyopathy
amyloidosis
sarcoidosis
hemochromatosis
scleroderma
fibrosis
ca
infiltrative process -> stiff heart muscle
restrictive cardiomyopathy
5 echo findings of restrictive cardiomyopathy
normal EF
normal heart size
large atria
normal LV wall
early diastolic filling
tx for restrictive cardiomyopathy
diuretics
acei
ccb
3 PE findings of CHF
S3
crackles
displaced apical impulse
4 mcc of CHF
CAD
HTN
MI
DM
CHF leads to _ remodeling, which causes dilation, thinning, _ valve incompetence, and _ ventricle remodeling
left ventricle
mitral valve
right ventricle
6 sx of CHF
exertional dyspnea -> dyspnea at rest
chronic, nonproductive cough
fatigue
orthopnea
nocturnal dyspnea
nocturia
PE findings associated w. CHF (8)
cheyne stokes breathing
edema
rales
S3/S4
JVD > 8 cm
cyanosis
hepatomegaly
jaundice
S4 heart sound is associated w.
diastolic HF
presrved EF
pathologic S3 heart sound is associated w.
systolic HF
reduced EF
NY HF classification
class 1: no PA limitation
class 2: slight PA limitation, comfortable at rest
class 3: marked PA limitation, comfortable at rest
class 4: can’t carry on PA, angina at rest
dx for CHF (4)
BNP
EKG
CXR
echo
gs dx for CHF
echo
what is this showing
kerley lines -> CHF
tx for CHF systolic vs diastolic
systolic: ACEI, bb, diuretics
diastolic: ACEI, bb, CCB
2 causes of CAD
vasospastic (prinzmetal)
atherosclerotic dz
rf for CAD
smoking
DM
dyslipidemia
HTN
fam hx
men > 55
women > 65
dx for CAD
high sensitivity CRP
lipids/TG
carotid US
primary preventive tx for CAD
PLT inhibitors: ASA, clopidogrel
secondary prevention for CAD
ASA
bb
ACEI/ARB
nitro
atherosclerosis is due to _ cells that are attracted to lipids on the cell wall, and trigger cytokine release
foam cells (dead macrophages)
_ plaque is stable
_ plaque is easily ruptured
thick: stable
thin: easily ruptured
steps in plaque bulid up
- adhesion
- activation
- aggregation
- propagagion
- PLT adherence
inflammation of the heart lining or heart valves caused by bacteria in the bloodstream
endocarditis
what 3 procedures increase risk for endocarditis
dental
intestinal
urinary tract
2 hallmark sx of endocarditis
fever
PLUS
new murmur
pathogen associated w. endocarditis:
acute:
subacute:
IVDU:
prosthetic valve:
acute: s. aureus
subacute: s. viridans
IVDU: s. aureus
prosthetic valve: staph epidermidis
duke’s criteria
2 major
OR
1 major PLUS 3 minor
OR
5 minor
3 major duke criteria
2 positive cultures 12 hr aprt
echo findings
new murmur
minor duke criteria
from jane:
fever > 100.5
roth spots
osler nodes
murmur
janeway lesions
anemia
nail bed hemorrhages
emboli
valve associated w. endocarditis in IVDU vs non drug users
IVDU: tricuspid
non IVDU: mitral
what is this showing
painless lesions on the palms/soles -> janeway lesions
what is this showing
raised, painful, tender nodule -> osler node
what is this showing
exudative lesions on the retina -> roth spots
2 nail findings of endocarditis
clubbing
splinter hemorrhages
tx for endocarditis:
empiric:
prosthetic valve:
pre procedure prophylaxis:
empiric: vanco OR amp/sulbactam PLUS aminoglycoside
prosthetic valve: same as empiric, add rifampin
pre procedure prophylaxis: amoxicillin
murmurs to know (7)
aortic stenosis
aortic regurgitation
mitral stenosis
mitral regurgitation
MVP
tricuspid stenosis
tricuspid regurgitation
pulmonary regurgitation
harsh systolic ejection crescendo decrescendo murmur heard best at the USB
aortic stenosis
aortic stenosis murmur radiates to the
neck
apex
sx of aortic stenosis
dyspnea
angina
syncope w. exertion
aortic stenosis murmur increases w.
squatting
soft, high pitched blowing crescendo decrescendo murmur best heard along LSB
aortic regurgitation
what increases the murmur of aortic regurgitation
leaning forward
water hammer pulse
large/bounding arterial pulse -> aortic regurgitation
diastolic low pitched decrescendo rubling w. an opening snap heard best at the apex
mitral stenosis
mitral stenosis murmur is best heard w. the pt in the _ position
left lateral decubitus
mcc of mitral stenosis
rheumatic fever
blowing holosystolic murmur heard best at the apex
mitral regurgitation
mitral regurgitation murmur radiates to the
left axilla
5 causes of mitral regurgitation
CAD
HTN
MVP
rheumatic fever
heart valve infxn
midsystolic ejection click heard best at the apex
MVP
mid diastolic rumbling murmur at LLSB w. opening snap
tricuspid stenosis
high pitched holosystolic murmur at LLSB that radiates to the sternum
tricuspid regurgitation
the murmur of tricuspid regurgitation increases w.
inspiration
harsh, loud medium pitched systolic murmur heard best at the 2nd/3rd intercostal space
pulmonary stenosis
high pitched early diastolic decrescendo murmur at LUSB that increases w. inspiration
pulmonary regurgitation
screening guidelines for HLD:
USPSTF vs NCEP
USPSTF: start at 35 yo
NCEP: start at 20 yo
4 groups most likely to benefit from statins
any form of ASCVD
LDL > 190
DM, 40-75 yo, LDL 70-189
40-75 yo w. ASCVD >/= 7.5%
what are the 2 high intensity statins
atorvastatin 40, 80 mg
rosuvastatin: 20, 40 mg
definition of primary HTN
2 readings on 2 separate visits w. no identifiable cause:
SBP >/= 130
OR
DBP >/= 80
adult HTN classifications
normal: <120/80
elevated: 120-129 AND < 80
stage 1: 130-139 OR 80-89
stage 2: >/= 140 OR >/= 90
ACC/AHA BP targets
<130/80
HTN tx based on classificaiton
-normal: lifestyle, evaluate annually
-elevated: lifestyle, re-evaluate 3-6 mo
-stage 1 and <10% ASCVD risk: lifestyle, re-evaluate 3-6 mos
-stage 1 and >10% ASCVD risk OR CVD, DM, CKD: lifestyle PLUS 1 med, re-evaluate in 1 month
-stage 2: lifestyle + 2 BP meds, re-evaluate in 1 month
first line pharm for HTN for non black pt
ACEI vs ARB
CCB (dihydropiridine)
HCTZ
tx for HTN for black pt’s
HCTZ
+
CCB
contraindication for bb
asthma
major s.e consideration for bb
ED
best med for htn + angina
ccb
t/f: ACEI are contraindicated in pregnancy
t!
common s.e of ccb
peripheral edema
best med for HTN plus BPH
alpha blockers
2 major s.e of hydralazine
lupus like syndrome
pericarditis
definition of htn emergency vs urgency
urgency: >180/120 w.o end organ damage
emergency: >180/120 + impending or progressing end organ damage
definition of malignant htn
DBP > 140
PLUS
papilledema, encephalopathy, or nephropathy
tx for htn urgency vs emergency vs malignant
urgency: clonidine
emergency: sodium nitroprusside
malignant: hydralazine
what are the 2 rate control ccb
verapamil
diltiazem
management of MI
bb
NTG
ASA and plavix
heparin
statins
reperfusion
door to balloon time goal for MI
90 mins
2 reperfusion options for MI
angioplasty
thrombolytic
4 contraindications for fibinolytic therapy
ICH
ischemic stroke in past 3 mos
confirmed or suspected dissection
active bleeding
indication for fibrinolytic therapy for MI
PCI not available
goal timing for fibrinolytic therapy
w.in first 3 hr
myocardial necrosis and rise in cardiac markers w.o complete coronary a blockage or ST elevation
NSTEMI
cardiac labs and when they become elevated w. MI
myoglobin: 1-4 hr
troponin: 2-4 hr
CK/CK-MB: 4-6 hr
mcc of myocarditis
viral infxn
3 causes of myocarditis
infxn
xrt
hypersensitivity
6 sx of myocarditis
fatigue
fever
chest pain
dyspnea
palpitations
tachycardia
gs dx for myocarditis
endomyocardial bx
severe complication of myocarditis
heart failure
45 yo M w. T1DM and ESRD on hemodialysis - dyspnea, cough, and CP that is worse during inspiration and when lying on back
pericarditis
10 causes of pericarditis
SLE
uremia
coxsackie virus
TB
RA
neoplasm
drugs
xrt
scleroderma
MI
pain w. pericarditis is relieved by (2)
sitting
leaning forward
heart sound associated w. pericarditis
pericardial friction rub
what is dressler’s syndrome
pericarditis 2-5 days after acute MI
ekg findings of pericarditis
diffuse ST elevations
echo findings of pericarditis
effusion
+/- tamponade
tx for pericarditis
nsaids
steroids if sx > 48 hr
abx
pericardiocentesis
head at 45 degrees
atherosclerotic dz of the lower extremities and vessels outside the heart/brain
peripheral vascular dz
mc presentation of PVD
intermittent claudication: intermittent pain brought on w. exercise and relieved w. rest
what is leriche syndrome
PVD in the iliac arteries
leriche triad
claudication
impotence
decreased femoral pulses
mc location for PVD
femoral a: thigh/upper calf claudication
claudication in lower calf indications PVD in what artery
popliteal
5 sx of PVD
weak/absent distal pulses
arterial bruits
loss of hair
shiny, atrophic skin
pallor w. dependent rubor
6 p’s of arterial embolism
pain
pulselessness
pallor
paresthesias
poikilothermia
paralysis
dx for PVD: initial vs gs
initial: ABI
gs: arteriography
what ABI indicates PVD
<0.9
mainstay pharm for PVD
cliostazol
all pharm options for PVD
bb
ACEI
statins
cliostazol
ASA
clopidogrel
surgical management of PVD
angioplasty/bypass
endarterectomy
mc location for varicose veins
greater saphenous
describe varicose veins
turguous
reticular
telangiectasias
management of varicose veins
wt loss
compression stockings
leg elevation
radiofrequency vs lasaer ablation
sclerotherapy
surgical stripping
what is this showing
phlebitis: inflammation of a vein near the surface of the skin
sx of phlebitis
dull pain
erythema
swelling/heat
PE sign associated w. phlebitis
homan’s sign: pain w. dorsiflexion of the foot
dx for phlebitis
US
venography
d dimer
management of phlebitis: superficial vs deep
superficial: bed rest, local heat, elevation, NSAIDs
deep: anticoagulation vs surgery
4 sx of chronic venous insufficiency
progressive edema
itching
dull pain
ulcerations
shiny, thin, atrophic skin
complications of chronic venous insufficiency
ulcerations
management of chronic venous insufficiency
elevation
compression
inflammatory rxn to GAS that causes antistreptolysin abs to form
rheumatic fever
dx for rheumatic fever
e.o recent GAS infxn PLUS Jones criteria:
2 major
OR
1 major and 2 minor
major jones criteria
joint pain (poly)
(o) carditis
nodules
erythema marginatum
sydenham’s chorea
minor jones criteria
mono arthralgia
elevated ESR/CRP
fever
prolonged PR
tx for rheumatic fever
ASA vs NSAIDs
steroids
abx
post rheumatic fever antistreptococcal prophylaxis guidelines
pen g ->
kids w.o carditis: up to 5 yr or til 21 yo
kids w. carditis w.o residual heart damage: 10 yr
kids w. carditis and e.o heart damage: indefinitely
consequence of rheumatic fever that causes inflammation and scarring of the heart valves
rheumatic heart dz
rheumatic heart dz mc affects the _ valve
mitral
what protein is associated w. rheumatic fever/heart dz
m protein
rheumatic heart dz is a type __ hypersensitivity
II
complication of rheumatic heart dz: early vs late
early: mitral regurgitation
late: mitral stenosis
onset of rheumatic heart dz sx occurs _ yrs after rheumatic fever
10-20
sx of rheumatic heart dz
palpitations
dyspnea
mitral regurg/stenosis
aortic regurg/stenosis
dx for rheumatic heart dz
echo
anti streptolysin O (ASO) titers
histology
histology findings of rheumatic heart dz
aschoff bodies on heart valves (granulomas w. giant cells)
pharm for GAS prophylaxis if pcn allergy
sulfadiazine
early murmur suggests
regurgitative flow (usually aortic)
rumbling murmur suggests
stenosis (usually mitral)
mc type of murmur
midsystolic (ejection)
describe ejection murmurs
peak near mid systole
stop before S2
gap between murmur and S2
4 ejection/midsystolic murmurs to know
aortic stenosis
pulmonic stenosis
HOCM
MVP
systolic ejection crescendo decrescendo murmur heard best in the RUSB
aortic stenosis
hard midsystolic ejection crescendo decrescendo murmur w. widely split S2 at LSB
pulmonic stenosis
pulmonic stenosis murmur radiates to the
left shoulder
neck
the HOCM murmur increases w. _
and decreases w. _
increases: straining
decreases: squatting
midsystolic ejection click at the apex
MVP
3 pansystolic murmurs to know
mitral regurgitation
tricuspid regurgitation
VSD
blowing holosystolic murmur at the apex w. a split S2
mitral regurgitation
high pitched holosystolic murmur at the mid LSB
tricuspid regurgitation
harsh holosystolic murmur heard at LSB w. wide radiation and fixed split S2
VSD
who should get screened for aortic aneurysm
> 65 yo male
hx smoking
management of aortic aneurysm
> 3 cm: monitor annually
4 cm: bb
5.5 cm or 0.5 cm expansion/year: surgery
management of aortic dissection
ascending: surgical emergency
descending: bb
gs dx for arterial embolism
angiography
management of arterial embolism
IV heparin
angioplasty vs graft vs endarterectomy
inflammation of large and medium vessels
giant cell arteritis
5 sx of giant cell arteritis
jaw claudication
HA
thickened temporal a
ttp of scalp
amaurosis fugax
amaurosis fugax is caused by
anterior ischemic optic neuritis
dx for giant cell arteritis
ESR > 100
temporal a bx
management of giant cell arteritis
prednisone ASAP
palpable cord makes you think of
phlebitis/thrombophlebitis
ulcers caused by venous insufficiency are mc located
above the medial malleolus
initial vs dx for venous thrombosis
initial: US
gs: venography
tx for venous thrombosis
heparin to coumadin bridge
which 3 murmurs are holosystolic
mitral regurgitation
tricuspid regurgitation
VSD
which 4 murmurs are midsystolic
aortic stenosis
pulmonic stenosis
HOCM
ASD
MVP