Infectious diarrhoea Flashcards

1
Q

What is viral gastroenteristis

A

Acute inflammation of lining of stomach and small intestine from viral infection

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1
Q

Most common causative organ in children vs adults viral diarrhoea

A

Norovirus in adults
Rotavirus in children

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2
Q

Management of viral gastroenteritis

A

Assessing for features of dehydration and shock - fluid resus if severe
Consider need for hospital admission
Enabling rehydration and electrolyte replacement
Prevent spread of infection

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3
Q

When need urgent fluid resuscitation

A

Systolic blood pressure <100
Heart rate >90
Cool peripheries
Respiratory rate >20
NEWS score >5

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4
Q

When admit someone to hospital with viral diarrhoea

A

If they are unable to to maintain oral intake due to vomiting
Some elderly individuals >60 years old, who are more at risk of severe dehydration
Abdominal tenderness
Diarrhoea lasting 10 days or more

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5
Q

What complication of Ecoli diarrhoea can be life threatening

A

Haemolytic uraemic syndrome

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6
Q

Definition of diarrhoea

A

> 3 loose or watery stools a day
<14 days acute diarrhoea, >14 = chronic diarrhoea

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7
Q

What is travellers diarrhoea

A

at least 3 loose or watery stools in 24 hours with or without one or more of abdominal cramps, fever, nausea, vomitting or blood in the stool

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8
Q

Acute food poisonning causes

A

Staphylococcus aureus, Bacillus cereus or Clostridium perfringens.

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9
Q

What type of diarrhoea does giardiasis cause

A

Prolonged non bloody

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10
Q

How does E coli spread

A

Infected faeces, unwashed saladsm contaminated water

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11
Q

Toxin in e coli diarrhoea and what causes

A

Shiga toxin -> abdo cramps, bloody diarrhoea and vomitting

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12
Q

Why avoid antibiotics in ecoli diarrhoea

A

Increase risk of HUS

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13
Q

What is campylobacter and how is it spread

A

Gram negative bacteria curved or spiral shaped
Raw or improperly cooked poultry
Untreated water
Unpasteurised milk

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14
Q

Symptoms of campylobacter

A

Abdominal cramps
Diarrhoea often with blood
Vomiting
Fever

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15
Q

INcubation and resolution time campylobacter

A

2-5 days incubation
3-6 day symptom resolution

16
Q

What is treatemnt for campylobacter diarrhoea

A

Antibiotics if successfully isolate and severe symptoms or risk factors eg HIV, HF
Clarithromycin
Azithromycin and ciprofloxacin 2nd line

17
Q

INcubation and length of shgella diarrhoea

A

1-2 days incubation
Resolved within week

18
Q

Salmonella incubation and length of illness

A

12 hour to 3 days incubation
Symptoms resolve in one week

19
Q

What causes bacillue cereus

A

Gram + rod
Spread through contaminated cooked food - grows if not refrigerated
-> cereulide

20
Q

Onset and length of bacillue cereus

A

5 hour incubation vomitting
Diarrhoea after 8 hurs
Resolves within 24 hours

21
Q

What causes yersinia infection

A

Gram negative baccillus
Pigs are key carriers - raw or undercooked pork

22
Q

Yersinia incubation and length of infection

A

4-7 dyas
>3 weeks of symptoms

23
Q

What infectious diarrhoea can be istaken for appendicitis and whty

A

Yersinia - R sided abdo pain due to mesenteric lymphadenitis

24
Staph aureus onset and reolution diarrhoea
Eggs, dariry and meat enterotoxins Start within hours of ingestion, settle in 12-24 hours
25
Giardiasis transmission
Parasites release cysts in faeces-> food or water Chronic diarrhoea
26
Diagnosis of giardiasis
NAAT or EIA testing stool
27
Treatment giardiasis
Tinidazole Metronidazole
28
Incubation period of all infectious diarrhoeas
1-6 hrs: Staphylococcus aureus, Bacillus cereus* 12-48 hrs: Salmonella, Escherichia coli 48-72 hrs: Shigella, Campylobacter > 7 days: Giardiasis, Amoebiasis
29
Amoebiasis presenations
Gradual onset bloody diarrhoea, abdominal pain and tenderness which may last for several weeks
30
What does less than 6 hour onset of symptoms from food suggest
Preformed toxin eg bacillus cereus or staph aureus
31
red flags in acute diarrhoea
Blood in the stool, which is usually seen with invasive pathogens or severe inflammation, e.g. ulcerative colitis. Recent hospital treatment or antibiotic treatment. Weight loss. Evidence of dehydration. Nocturnal symptoms — organic cause more likely. sexual history (particularly in MSM) to exclude sexually transmitted enteric infection.
32
HOW LONG does diarrhoea from protazoa tend to be
over 14 days
33
Causes of bloody diarrhoea
Bacterial: Campylobacter jejuni, Salmonella, Escherichia coli O157:H7, Vibrio parahaemolyticus, Shigella, Yersinia, Aeromonas, Clostridioides difficile. Viruses: cytomegalovirus. Parasites: Entamoeba histolytica, schistosomiasis