Infectious and Derm Flashcards

1
Q

HIV treatment

A

2 NRTIs + 1 of integrase inhibitor (INI), a non-nucleoside reverse transcriptase inhibitor (NNRTI), or a boosted protease inhibitor (PI)

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2
Q

List of NRTIs and side effects

A

emtricitabine, tenofovir disoproxil or tenofovir alafenamide, abacavir and lamivudine.

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3
Q

Chlamydia treatment

A

doxycycline 100 mg b/d 7
azithromycin 1 g 1 day, 500 mg - 2days
erythromycin 500 mg twice daily for 10–14 days
If pregnant : Azithromycin
Erythromycin
Amoxicillin

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4
Q

schistosoma haematobium associated cancer

A

SCC of the urinary bladder

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5
Q

CNS Cryptococcosis symptoms

A

meningoencephalitis n immunocompromised

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6
Q

CNS India ink test positive

A

cryptococcal meningitis

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7
Q

flexural psoriasis

A

Topical steroids

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8
Q

Acanthosis nigricans (AN) cancer

A

gastric adenocarcinoma

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9
Q

Strongyloides

A

Ivermectin

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10
Q

Visceral leishmaniasis

A

Sodium stibogluconate

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11
Q

Cancer related to PUWA theraphy

A

SCC

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12
Q

Guttate psoriasis treatment

A

UVB

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13
Q
A

CD4 count (cells per microlitre) Risk of opportunistic infection Risk of HIV-related cancers Direct HIV effects
500 and below Little risk Hodgkin’s lymphoma
Cervical cancer
400 and below Bacterial skin infections Lymphadenopathy
Recurrent bacterial chest infections Sweats
Tuberculosis
Oropharyngeal candida
Fungal infections
Seborrhoeic dermatitis
350 and below Oral hairy leukoplakia Non-Hodgkin’s lymphoma Weight loss
Shingles
Pneumocystis pneumonia
Persistent herpes simplex infection
200 and below Oesophageal candida Kaposi’s sarcoma Diarrhoea
Histoplasmosis Wasting
Cryptococcal meningitis
Cerebral toxoplasmosis
Cryptosporidiosis
100 and below Cytomegalovirus infections Primary cerebral lymphoma Dementia
Atypical mycobacterium infections

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14
Q

antibiotic promote MRSA

A

Cipro

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15
Q

Lupus Pernio associated

A

Sarcoidosis

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16
Q

Lupus Vulgaris

17
Q

low CSF glucose, viral picture

18
Q

SJS drugs

A

HIV, malignency, penicillin, sulphonamide, allopurinol, anti-epileptic

20
Q

Coombs test positive

A

direct antiglobulin test
haemolitic anemia immune mediated

21
Q

mycoplasma diagnosis

22
Q

dissiminated gonc infection triad

A

dermatitis, tenosynovitis and migratory polyarthritis.{young man}

23
Q

violaceous papules on the flexor aspects of her wrists, itchy and polygonal

A

lichen planus

24
Q

Strongyloides treatment

A

Ivermectin

25
Q

schistosomiasis treatment

A

praziquantel

26
Q

Dermatitis herpetiformis

A

IgA antibodies deposited in dermis

28
Q

Quinine-induced thrombocytopenia (QITP)

A

a condition where quinine, a drug used to treat malaria and leg cramps, can cause a decrease in platelets (thrombocytopenia) due to the formation of antibodies that recognize platelet membrane glycoproteins

associated with hemolytic uremic syndrome (HUS)
Quinine-dependent antibodies have been shown to react with red cells and granulocytes, potentially contributing to the development of HUS

management - stopping quinine and supportive care (platelet)