Infections of the Reproductive

Question 1

Herpes Simplex Virus Types 1 and 2
CHARACTERISTICS

Answer 1

• enveloped virus with
• icosahedral nucleocapsid and
• linear double-­‐stranded DNA

Question 2

TRANSMISSION
– HSV-­‐1:

Answer 2

saliva
or
direct

Question 3

Transmission of HSV-2

Answer 3

sexual
or
transvaginal

Question 4

What is the site of latency in HSV-1:

Answer 4

trigeminal ganglia

Question 5

What is the site of latency in HSV-2

Answer 5

lumbosacral
ganglia

Lover is composed of 2

Question 6

When HSV is smeared what is seen in Tzank smear?

Answer 6

multinucleated
giant
cells

Question 7

What is Cowdry type A) in HSV

Answer 7

large,
pink
to
purple
intranuclear
inclusions

Question 8

Herpes Simplex Virus Type 1

SPECTRUM
OF
DISEASE

Answer 8

• gingivostoma&&s
• § herpes labialis (lips)
• § keratoconjunc&vi&s
• § temporal lobe encephalitiss
• § herpeticc whitlow (fingers)
• § herpes gladiatorum (trunk)

Question 9

What do you call the Disease when HSV cause it in fingers?

Answer 9

herpetic whitlow

Question 10

What do you call the HSV that cause in trunk?

Answer 10

herpes
gladiatorum

Question 11

neonatal herpes is due to

Answer 11

contact with birth canal

Question 12

genital
herpes
– painful
anogenital
vesicles

Question 13

Herpes Simplex Virus
Types 1 and 2
TREATMENT

Answer 13

DOC
is
Acyclovir

Question 14

What is the function of Acyclovir?

Answer 14

• shortens the duration of the lesions
• reduces the extent of shedding of the virus
• no effect on the latent state

Question 15

Neisseria
gonorrhoeae
CHARACTERISTICS

Answer 15

• gram-­‐negative “kidney-­‐ bean” diplococci
• insignificant capsule
• Oxidase-­‐posi9ve colonies on Thayer-­‐MarDn medium

Question 16

Neisseria
gonorrhoeae
HABITAT

Answer 16

human
genital
tract

Question 17

Neisseria
gonorrhoeae

TRANSMISSION

Answer 17

sexual
contact
or
during
passage
through
birth
canal

Question 18

Neisseria
gonorrhoeae
PATHOGENESIS factors

Answer 18

• pili
• § lipo-­‐oligosaccharide (LOS)
• § IgA protease
  § complement deficiencies in the late-­‐acting complement components (C6C9) predispose to illness
  
  • cannot form membrane-attack complexes
    *

Question 19

Neisseria
gonorrhoeae is usual coinfction with

Answer 19

Chlamydia
trachomatis

Question 20

Neisseria
gonorrhoeae
SPECTRUM
OF
DISEASE:
Localized

Answer 20

• OPHTHALMIA NEONATORUM
• GONOCOCCAL URETHRITIS
• PELVIC INFLAMMATORY DISEASE
• SEPTIC ARTHRITIS

Question 21

purulent
conjunctivitis
in
newborns

Answer 21

OPHTHALMIA
NEONATORUM

Question 22

urethritis and epididymis in men

– most common cause of urethritis

Answer 22

GONOCOCCAL
URETHRITIS

Question 23

– most common cause of
PID

Answer 23

N.gonorrhea

Question 24

Neisseria gonorrhoeae

PELVIC INFLAMMATORY DISEASE complications:

Answer 24

• sterility
• • ectopic pregnancy
• • chronic pelvic pain
• • dyspareunia
• • Fitz-­‐Hugh-­‐Curtis syndrome (perihepatitis)
  
  • – violin-­‐string adhesions

Question 25

most common cause in sexually active adults arthri9s, tenosynovitis, or pustules in the skin

Answer 25

SEPTIC ARTHRITIS

Question 26

What is the treatment of N. gonorrhea?

Answer 26

Ceariaxone + Doxycycline due to frequent coinfecTIon with Chlamydia trachoma.s