Infections Flashcards

1
Q

HSV/VZV

Histology

A
  1. ballooned keratinocytes
  2. multinucleated keratinocytes
  3. peripheral margination of chromatin
  4. steel gray nuclei
  5. epidermal +/- follicular necrosis
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2
Q

Molluscum contagiosum

A

Molluscum bodies (eosinophilic intracytoplasmic inclusions)

Poxvirus

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3
Q

Verruca vulgaris

Histology

DDX

A

Histology:

  1. Verrucous epidermal hyperplasia
  2. HK
  3. PK
  4. Stratum corneal hermorrhage
  5. Prominent keratohyaline granules
  6. HPV

DDX: verrucous SK, atypical squamous proliferation, verrucous SCC

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4
Q

Dermatophytosis and tinea versicolor

A
  1. Spong derm
  2. sandwich sign
  3. bullet holes
  4. short hyphae and spores
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5
Q

Candidiasis

A

Septate pseudohyphae

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6
Q

Chromoblastomycosis

A

Medlar bodes look like copper pennies

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7
Q

Cryptococcus

A

Large, intracellular yeast-like

Mucin stains capsule

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8
Q

Staph scalded skin syndrome

A

Cell-poor bullae

No organisms

very superficial cleavage within or just below granular layer

toxin mediated

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9
Q

Histoplasma capsulatum

Histology

DDX

A

Histology:

  1. Small intracytoplasmic organisms with surrounding clear halo
  2. PAS and GMS+

DDX

  1. Leismaniasis (kinetoplast); Giemsa +
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10
Q

Scabies

A

intracorneal burr with mite

prominent dermal eos

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