Infection part 3 Q 100-150 Flashcards
Q100: Examples of cephalosporins
1st: Cefalexin, cefradine, cefadroxil…
Q101: How do cephalosporins work?
Prevent peptidoglycan buildup.
Q102: Conditions for cephalosporins
Septicaemia, pneumonia, meningitis…
Q103: Cephalosporins like which group?
Other beta-lactams: Penicillins…
Q104: Cephalosporins side effects
Diarrhea, Hypersensitivity…
Q105: Penicillin allergy in cephalosporins
1st gene 10%, 3rd gene 2-3%.
Q106: Cephalosporin generations
1st, 2nd, 3rd generation, colitis…
Q107: Examples of glycopeptide antibiotics
Vancomycin, teicoplanin…
Q108: How do glycopeptide antibiotics work?
Inhibit cell wall synthesis.
Q109: Uses of glycopeptide antibiotics
C.Diff, Endocarditis, MRSA…
Q110: Glycopeptide antibiotics side effects
Red man syndrome, Ototoxicity…
Q111: Vancomycin contraindications
History of hearing loss.
Q112: Vancomycin route of administration
IV preferred, oral for C. diff.
Q113: Vancomycin therapeutic range
Pre-dose 10-20mg/L, MIC ≥1mg/L 15-20mg/L
Q114: Monitor when taking vancomycin
Body weight, serum-vanc conc, FBC…
Q115: Vancomycin drug interactions
Nephrotoxicity with aminoglycosides…
Q116: Uses of clindamycin
BV, Acne, Diabetic foot infection…
Q117: How does clindamycin work?
Slows/stops bacterial growth.
Q118: Clindamycin side effects
Antibiotic-associated colitis, abdominal pain…
Q119: Clindamycin contraindications
Diarrhoeal states.