Infection/Inflammation Flashcards

1
Q

What is conjunctivitis?

A

Inflammation of conjunctiva (layer covering sclera and inner eyelids)

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2
Q

How does conjunctivitis present?

A

Red eye
Discharge
Foreign body sensation

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3
Q

What does a red eye with a sticky discharge suggest?

A

Bacterial conjunctivitis

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4
Q

What does a red eye with a watery discharge suggest?

A

Viral conjunctivitis

if itch present, allergic conjunctivitis

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5
Q

What does a red eye with watery, itchy discharge suggest?

A

Allergic conjunctivitis

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6
Q

What is papillary conjunctivitis and what does it suggest?

A

Conjunctivitis forming small red dots on inner surface of eye lids

Bacterial conjuncitivits

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7
Q

What is follicular conjunctivitis and what does it suggest?

A

Conjunctivitis forming avascular white nodules on eyelid

Viral/chlamydial conjuncitvitis

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8
Q

What organisms commonly cause bacterial conjunctivitis?

A

Staph. aureus
Strep. pneumoniae
H. influenzae

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9
Q

What is the treatment of bacterial conjunctivitis?

A

Chloramphenicol

Gentamicin if pseudomonas

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10
Q

What does follicular conjunctivitis with scarring suggest?

A

Chlamydial conjuncitvitis

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11
Q

What would make you consider chlamydial conjunctivitis?

A

Persistent conjunctivitis unresponsive to treatment

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12
Q

What is the management of chlamydial conjunctivitis?

A

Topical oxytetracycline

Full STI work up

Oral azithromycin if genital chlamydia infection

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13
Q

What is keratitis?

A

Inflammation of the cornea (transparant layer covering the anterior chamber)

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14
Q

How does keratitis present?

A
Sharp pain
Photophobia
Red, watery eye
Hypopyon (bacterial)
Dendritic ulcer (herpes)
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15
Q

What can cause keratitis?

A

Infection (bacterial, viral, fungal, parasitic)

Systemic disease (RA, Graves disease, Sjogren’s syndrome)

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16
Q

How is bacterial keratitis managed?

A

Hospital admission

Hourly antibiotic drops (olfaxacin and gentamicin-cefuroxime)

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17
Q

What treatment should not be used if a dendritic ulcer is present and why?

A

Steroids

Risks corneal melt and perforation

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18
Q

How is herpetic keratitis managed?

A

Aciclovir ointment (5 times daily)

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19
Q

Patient presents with a sharp pain in his eye with is red a week after suffering a URTI.

What is the diagnosis?

A

Adenoviral keratitis

20
Q

Who is predisposed to developing fungal keratitis?

A

Africans

Immunocompromised

21
Q

What parasite can cause keratitis with inappropriate contact lens wear?

A

Acanthamoeba keratitis

22
Q

What treatment will show corneal abrasion?

A

Fluorescein stain

23
Q

What inflammatory eye condition is associated with systemic conditions?

Name 3

A

Anterior uveitis

Ankylosing spondylitis (HLA-B27)
Inflammatory bowel disease
Sarcoidosis
24
Q

What is anterior uveitis?

A

Inflammation of the iris and anterior chamber

25
How does anterior uveitis present?
Eye pain Red eye (circumcorneal and injection) Photophobia Cells/flare in anterior chamber Hypopyon
26
How is anterior uveitis managed?
Hourly topical steroids Twice daily mydriatic
27
What is anterior blepharitis?
Inflammation of eyelid causing a red lid margin
28
What is posterior blepharitis?
Inflammation of meibonian gland causing chalazia (cyst) formation under eyelids
29
What are the two classes of anterior blepharitis and how do they differ?
Seborrhoeic - basically seborrhoeic dermatitis of eyelids (causes red lid margin with scaling but no eyelash dysfunction) Staphylococcal - staph infection of eyelash follicle (causes red lid margin with styes and dysfunctional eyelash growth)
30
What condition is posterior blepharitis strongly associated with?
Rosacea
31
What is chorioretinitis?
Inflammation of choroid and retina
32
What can cause chorioretinitis?
Toxoplasma Toxocariasis Cytomegalovirus
33
What is cytomegalovirus chorioretinitis associated with?
AIDS
34
What is endopthalmitis?
Sight threatening and potentially devastating infection of the inner eye
35
How does endopthalmitis present?
Severe pain Very red eye Decreasing vision
36
How is endopthalmitis managed?
Intravitreal antibiotics (amikacin, cefatazidime, vancomycin)
37
What is episcleritis?
Non-serious inflammation of the episclera (layer between sclera and conjunctiva)
38
What is the management of episcleritis?
Nothing | self-limiting condition
39
What is scleritis?
Inflammation of the sclera
40
How does scleritis present?
Severe eye pain | Violaceous vessel injection
41
How is scleritis managed?
Oral NSAIDs and steroids
42
What is orbital cellulitis?
Infection of tissues around the orbital septum (membranous sheet preventing spread of infection into orbit)
43
How does orbital cellulitis present?
Erythema and oedema around the orbit Pain on eye movements
44
How is orbital cellulitis managed?
1. MRI to assess whether pre/post septal cellulitis and source of infection (e.g. ethmoid sinus or chalazion) 2. Broad spectrum antibiotics 3. Drain any abscesses
45
What are the two classifications of orbital cellulitis? Which of these is more serious?
Pre-septal (infection anterior to orbital septum) Post-septal (infection posterior to orbital septum) Post-septal is much more serious as it is sight threatening
46
What eye condition is often assosiated with rheumatoid arthritis and granulomatosis with polyangiitis (GPA)?
Scleritis