Infection 💊 (Antibiotics) Flashcards
What is an example of a cephalosporin?
Cefalexin
What are two of the main sub-groups of beta-lactams?
Penicillins and cephalosporins
How do beta-lactams work as antibiotics?
Interferes with the synthesis of bacterial cell wall peptidoglycan so bacteria cant make rigid cell walls
What are common examples of penicillins?
Amoxicillin, co-amoxiclav, flucloxacillin, penicillin V
What is the function of the enzyme that clavulanic acid inhibits?
Beta-lactamase is an enzyme bacteria use to break down beta-lactam antibiotics
What is combined with amoxicillin to create co-amoxiclav?
Clavulanic acid
What are three groups of antibacterial that affect bacterial protein synthesis?
Tetracyclines, macrolides, nitrofurans
what is an example of a quinolone?
Ciprofloxacin
What is an example of a tetracycline?
Doxycycline
What are examples of macrolides?
Clarithromycin, azithromycin
How does trimethoprim work as an antibacterial?
Interferes with folate synthesis
What class of drug is aciclovir?
Anti-viral
What are the broad-spectrum antibiotics most commonly associated with C. Difficile infection?
Quinolones and cephalosporins
What are some common indications for tetracyclines?
Acne vulgaris, lower respiratory tract infections, chlamydia infection
What is the mechanism of action of tetracyclines?
They inhibit bacterial protein synthesis by binding to the ribosomal 30S subunit
