Infection And Response Flashcards

1
Q

Communicable disease

A

Caused by pathogens such as bacteria and viruses that can be passed from person to person

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2
Q

Bacteria

A

Single-celled living organisms

Split in two and produces toxins

Reproduce rapidly

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3
Q

Bacterial diseases - gonorrhoea

A

A sexually transmitted disease (STD) caused by a bacterium

Pain when urinating, yellow discharge

To prevent infection people can abstain from sex

Antibiotics against gonorrhoea

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4
Q

Bacterial diseases - salmonella

A

A bacteria that causes food poisoning

Often found in unhygienic kitchens, undercooked foods, or the same foods that have not been reheated properly

All poultry is vaccinated against it to stop the spread

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5
Q

Virus

A

Very, very small and have a regular shape

Take over the cells of your body to reproduce, causing damage and destroying cells

Reproduce rapidly

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6
Q

Viral diseases - tobacco mosaic virus

A

Transmitted by contact between plants, either naturally or through the hands of farmers

Effects the chloroplasts - changing colour from green to yellow/white

Reduces ability to photosynthesise and reduces crop yields

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7
Q

Viral diseases - HIV/AIDS

A

Transmitted by body fluids, often during unprotected sex, but also through cuts and injecting drugs using shared needles

After infection, people often suffer mild flu-like symptoms

AIDS is the last stage of HIV - attacks the immune system

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8
Q

Viral diseases - measles

A

Transmitted through the air in tiny droplets after an infected person sneezes

Children develop a fever and a rash

There are vaccines against measles

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9
Q

Protists

A

A eukaryotic, usually a single-celled, organism

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10
Q

Protist diseases - malaria

A

Spread by mosquitoes

Causes a fever and a rash

Spread of malaria is controlled by preventing the vectors, mosquitos, from breeding and by using mosquito nets to avoid being bitten

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11
Q

Fungi

A

A large group of eukaryotic organisms that contain single-celled yeasts, moulds and mushrooms

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12
Q

Fungal diseases - rose black spot

A

Transmitted in air or water, as well as through direct contact by gardeners

Infects leaves and causes black or purple spots on the leaves, the rest of the leaves often turn yellow and can drop off the plant

Treated using fungicides and removing infected plants

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13
Q

Natural barriers to pathogens

A

Chemical in tears

HCl acid in stomach

The skin on our body

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14
Q

Preventing spread of pathogens

A

Isolate those infected

Destroying vectors that carry the disease

Vaccinations

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15
Q

White blood cells

A

Ingest pathogens (phagocytosis)

Produce antibodies

Produce antitoxins

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16
Q

Vaccinations

A

A dead or altered form of the disease causing pathogen to be introduced into the body, which contains a specific antigen

This causes white blood cells to produce complementary white blood cells

17
Q

Herd immunity

A

The protection given to a population against an outbreak of a specific disease when a very high percentage of the population has been vaccinated against it

18
Q

Antibiotics

A

Substance that controls the spread of bacteria in the body by killing them or stopping them reproducing

19
Q

Process of antibiotics

A

Antibiotics damage the bacterial cells but do not damage the host cells

They do not work on viral diseases as they reproduce inside host cells

20
Q

Antibiotics - penicillin

A

The first antibiotic was discovered in 1928 by Alexander Fleming when he noticed some bacteria in a petri dish was killed by penicillium mould

21
Q

Antibiotic resistance

A

The ability of bacteria to survive exposure to antibiotics, caused by mutations in their genes

22
Q

Reasons for antibiotic resistance

A

Overuse of antibiotics

Failing to complete the fully prescribed course by a doctor

23
Q

Painkillers

A

A chemical is taken to relieve pain associated with disease, but does not kill the pathogen

24
Q

Traditional drugs

A

Were extracted from plants and microorganisms

E.g. penicillium, digitalis (heart drug originated from foxgloves), painkiller aspirin (originated from a willow tree)

25
Modern drugs
Tested for efficacy, toxicity and dosage
26
Stages of drug testing
Preclinical trial (1) - drugs are tested on skin cells for efficacy and possible side effects Preclinical trial (2) - drugs are tested on animals for efficacy and possible side effects Clinical trials - drugs tested on healthy humans first (very low doses given)
27
Placebo
A 'dummy' treatment with no medical or therapeutic value
28
Double-blind trial
Neither the participants nor the researchers are aware which group has been given the drug and which group has been given the placebo
29
Monoclonal antibodies
Are identical copies of one type of antibody
30
Formation of monoclonal antibodies
An antigen is injected into a mouse The mouse naturally produces lymphocytes, which produce antibodies specific to the antigen Tumor cells which produce the lymphocytes are removed during a small operation They are fused forming hybridoma, which divides producing more hybridoma specific to the original antigen
31
Uses of monoclonal antibodies
Used in pregnancy tests Cancer treatment and diagnosis
32
Monoclonal antibodies in pregnancy tests
Pregnancy tests have been designed to bind with the hormone HCG found in the urine of pregnant women only Monoclonal antibodies are attached to the end of a pregnancy test stick onto which a woman urinates If she is pregnant, HCG will be present in her urine and will bind to the monoclonal antibodies on the test stick, causing a change in colour
33
Nitrate deficiencies in plants
The amount of chlorophyll in the plant reduces, reducing the amount of photosynthesis that occurs in the plant
34
Magnesium deficiencies in plants
Magnesium is used to make chlorophyll, compromising growth
35
Plant's defences against pathogens
Cellulose cell walls Tough waxy cuticle on leaves Layers of dead cells around stems (bark on trees) which fall off Antibacterial chemicals Poisons to deter herbivores Thorns and hairs deter animals