Infection And Response Flashcards

1
Q

What are pathogens

A

Microorganisms that cause communciable diseases. Bacteria,viruses,protists and fungi

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2
Q

What is bacetria and what do they do

A

Small prokaryotic cells that can infect both plants and animals

They reproduce rapidly in optimum conditions and release toxins that damage cells and tissue

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3
Q

What are viruses and what do they do

A

Don’t classify as living organisms because they rely on host cells to survive and reproduce

They insert genetic material into cells of infected organisms and use the cell to reproduce rapidly. This cause the cell to burst, releasing more viruses causing more infection.

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4
Q

What are prokaryotic cells and what do they do

A

Eukaryotic organisms that are often single-celled

They can live on or in a host organisms and cause them damage or transferred between hosts by organisms which don’t get the disease (vectors)

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5
Q

What is fungi and what does it do

A

It grows on living tissue and can be either single-celled or have a body made of hyphae

Hyphae penetrates living tissue,causing infections, and produce spores which allows infections to spread to other organisms

Fungal infections are mostly common in plants but a few animals can be infected

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6
Q

How do pathoegns spread

A

Air- some pathogens can be found in droplets from coughs or sneezes that are carried airbone and breathed by another organism.

Water-pathogens found in dirty water can be picked up by drinking or bathing in it

Direct contact- some pathogens can be acquired by touching contaminated surfaces or skin

Vectors- pathogens can be transferred between organisms by vectors

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7
Q

How can diseases become prevented

A

Coughing or sneezing in a tissue or a sleeve away from people

Washing your hands regularly with soap and hand hot water after using the toilet or before eating

Diseases spread by direct contact and air can be prveented by isolated the diseased individual

Spread of vector-borne diseases can be prevented by killing vectors carrying the disease (insecticides or detstroying their habitats)

Vaccinations prevent diseases spreading as they stop people and animals from developing the disease and pass it on

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8
Q

Viral diseases symptons and examples

A

Measles: spread by coughs snd sneezes (airborne)

Symptons: red skin rash and a fever

Teatment-vaccinations (no treatment)

HIV: spread through exchange of bodily fluids such sex and blood exchange

Symptoms: lead to aids, flu like symptons, damages the immune sympton

Treatment: antiretroviral drugs slow virus by preventing it attacking immunity cells

Tobacco Mosaic virus: plant virus

Symptons:distinct mosaic pattern visible on leaves, discolourlatipn of leaf limits photosynthesis

Treatment: isolate infected plants

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9
Q

Bacterial diseas symptons and examples

A

Salmonella: acquired by animals before death or invalid prep

Symptons:fever,abdominal cramps,vomiting and diarrhoea

Treatment: poultry vaccinated against salmonella to prevent disease

Gonorrhoea: an STD

Symptoms: thick yellow or green discharge from penis or vagina and pain when urinating

Treatment: spread of disease prevented using antibiotics and use of condoms

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10
Q

Fungal disease symptons and examples

A

Rose black spots disease: infects rose plants

Symptons: black/purple dots visible on leaves casuing them to turn yellow and fall, plants struggle to photosynthesise

Treatment:fungicides can be used to treat plants or infected leaves can be removed and destroyed

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11
Q

Protist disease symptons and examples

A

Malaria: caused by a protist that gets transported by a vector (mosquitos) life.

Symptons:repeated fever epsiodes that can be fatal

Teatment:stop mosquitos breeding and protecting people with mosquito nets and insecticides

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12
Q

What is a non specific defence and example and what they do

A

Defense system that defends the body against all pathogens

Skin: covers majority of body as a physical barrier to prevent pathogens from entering. Platelets form scabs by clotting blood to prevent pathogens from entering cute

Nose: hair and mucus act as a physical barrier and trap pathogens from entering through air.

Trachea and bronchi: goblets cells produce mucus and trap pathogens. Cila hairs waft mucus and pathogens up to the throat to be sent to the stomach

Stomach: contains very acidic hydrochloric acid that acts as a chemical barrier

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13
Q

What is a phagocytes and their function

A

A non-specific process by which phagocytes engulf and digest pathogens.

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14
Q

What is a lymphocyte and their function

A

Antigens on the pathogen detected by the lymphocyte. Antibodies produced with specific shapes that bind to the antigen causing it to clump to be easily digested by phagocytes

Memory lymphocytes left over incase the individual is infected in the future,

Antitoxins are also produced by lymphocytes to neutralise toxic substances produced by the pathogen stopping cell and tissue damage

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15
Q

What is a vaccination

A

Contains dead/weak forms of pathogens. Injected in the body to produce an immune response where lymphocytes produce antibodies to destroy it.

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16
Q

How do vaccinations prevent disease

A

Memory lymphocytes left over after they destroy the weak/damaged form of the pathogen by producing antigens foricng it to clump and engulfed by a phagocyte.

The memory lymphocytes will prodcue the correct antibodies to destroy the same pathogen

Pathogens destroyed before becoming infectious reducing spread of disease

17
Q

Advanatge of vaccines

A

Reduced occurence of diseases and eradicated others

Herd immunity prevents epidemics

18
Q

Disadvanatges of vaccines

A

Vaccines are not skways 100% effective at providing immunity

Side effects of different severities, from rashes to fevers

19
Q

What is a painkiller

A

Painkillers such as aspirin and paracetamol do not cure the disease itself so the body’s immune response destory the pathogen

20
Q

What is an antibiotic

A

A drug used to slow or stop the growth of harmful bacteria in the body it only works on bacteria

21
Q

How do antibiotics become resistsnt

A

1) random mutation happens in the genetic material of bacterial cells that make it resistant to a certain type of antibiotic

2) The bacteria survives the treatment and reproduces in the body carrying an increase of the resistant bacterial strain

22
Q

How to limit antibiotic resistance

A

Antibiotic resistance can evolve very quickly (binary fission) to slso the rate of development if resistsnt strains limit the use of antibiotics to more serious infections

23
Q

How were drugs made (origins)

A

From various plants and microorganisms

24
Q

How are drugs made now

A

Synthesied by chemists in labs. Drugs are based on the orginsl chemicals from plants and microorganisms

25
Q

Examples of drugs from other plant or microorganisms:

A

Alexand Fleming discovered pencillium mould=pencillin

Aspirin a painkiller derived from willow

Digitalis a heart drug originated form fox gloves

26
Q

What is done before giving drugs to humans

A

Thoroughly tested to ensure efficacy,safety and determine dosage. Investigation is then peer reviewed to check accuracy and legitimacy.

27
Q

What happens during preclinical trials

A

Drug is tested using computer model or is given to human cells cultured in lab for toxicity and efficacy

To detemine side effects and dosage the drugs are tested on animals.

28
Q

What happens during clinical trials (healthy group)

A

Healthy people tested first at low doses to ensure drug safety and to test for side effects in humans.

Does increased gradually to determine optimum dosage

29
Q

What happens during clinical trial (ill patients)

A

Ill patienst with disease tested to test efficacy and accurcay of dosage

Double blind trials used and after this testing it is appropriate for use

30
Q

What is a double blind trial

A

Patients are spit into 2 groups where 1 has been given the drug and the other has the placebo

Effect of trestment are observed

Neither patient nor doctor knows who has the trestment (no bias)

31
Q

Defien herd immunity

A

Herd immunity is when a large group is vaccinated to a certain pathogen so the select few who aren’t are safe from harm of the pathogen