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BNF > Infection > Flashcards

Infection Flashcards

1
Q

What are the hospital treatment for meningitis

A

Benzylpenicillin
Or
Cefotaxime

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2
Q

What are the antibiotics suitable for LOWER urinary tract infection MADCB

A 
Trimethoprim
Nitrofurantoin
Amoxicillin
Oral cephalosporins
For 3-7 d
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3
Q

What are the drugs used for tuberculosis

A 
Initial phase 4 drugs 
Isoniazid 
Rifampicin 
Ethambutol 
Pyrazinamide
For 2M

Maintainance phase 2 drugs:
Isoniazid
Rifampicin
For 4M

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4
Q

Linezolid spectrum

A

G+ve only
And anaerobes
MRSA

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5
Q

Linezolid used instead of… in MRSA INFECTION

A

Vancomycin

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6
Q

Se of linezolid

A

Blood disorder
Optic neuropathy if > 28 days use
Hypertensive crisis with SSRI TCA MAOI sumatriptan DA buspirone as linezolid is a reversible MAOI

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7
Q

What food to avoid when taking linezolid and why

A

Tyramine rich food bc linezolid is a reversible MAOI

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8
Q

Dose of trimethoprim for UTI

A

200BD

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9
Q

Se of Trimethoprim

A

1 teratogenic in first trimester as anti-folate
2 Blood dyscrasias with long-term use
3 Hyperkalaemia

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10
Q

What is the indication for co-Trimoxazole

A

Prophylaxis and treatment of pneumocystis jirovecii

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11
Q

What’s co trimoxaxole consist of

A

Trimethoprim / sulfamethoxazole

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12
Q

What are the side effects of co trimoxazole

A

Rash
SJS
photosensitive

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13
Q

Nitrofurantoin urine colour

A

Yellow or brown

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14
Q

Antibiotics that need to be taken with food

A

Metronidazole

Nitrofurantoin

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15
Q

Abx used for UTI

A

1st line nitrofurantoin/ trimethoprim
2nd pivemecillinam (penicillin)
Fosfomycin

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16
Q

Gentamicin multiple dose regimen - when to monitor serum level

A

after 3 or 4 doses or after a dose change

17
Q

gentamicin- how to manage in renal impair pt

A

increase dosing interval

18
Q

gentamicin- how to manage in SEVERE renal impair pt

A

reduce dose

19
Q

describe streptomycin

A

aminoglycoside, used as reserve for TB

20
Q

describe neomycin

A

the only aminoglycoside that is PARENTALLY TOXIC, only used in bowel sterilisation

21
Q

describe tobramycin

A

aminoglycoside used via inhaler for pseudo inf in cystic fibrosis - a hereditary disease, ex mucus in airway and GI cause lung inf and poor nutrition

22
Q

abx that most likely to cause GI colitis

A

clindamycin

23
Q

abx used to trt abx-related colitis (c.diff) and MRSA

A

vancomycin

24
Q

how to monitor serum vancomycin level

A

monitor after 3 or 4 doses and after dose change

25
Q

vancomycin pre-dose trough level

A

10-15mg/ml

26
Q

vancomycin pre-dose trough level for endocarditis or complicated SA inf

A

15-20mg/ml

27
Q

vancomycin infusion rate must be below x to avoid red man syndrome

A

< 10mg/ml

28
Q

abx to avoid when trting MRSA

A

quinolones eg cirpofloxacin

29
Q

s/e of quinolones

A
  1. seizure
  2. tendonitis
  3. arthropathy
  4. QT prolongation

BNF (13 decks)

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