Infection

Question 1

Sensorineural deafness
Cataracts
Congenital Heart Disease (PDA)

Risk greatest 8-10 weeks

Answer 1

Congenital Rubella Syndrome
- Sensorineural Deafness, Cataracts, PDA, Glaucoma

ALSO can be associated with:
- growth retardation, hepatosplenomegaly, purpura, salt and pepper chorioretinitis, micropthalmia, cerebral palsy

Question 2

Painful blisters affecting vagina and cervix

a. Genital Herpes
b. Ectropium
c. Molluscum Contagiosum
d. Syphyllis
e. Vulval Malignancy

Answer 2

Genital Herpes

• In pregnancy, oral aciclovir should be continued til delivery and delivery should be via caesarean section

Question 3

Management for VZV exposure in a previously unexposed pregnant woman

Answer 3

VZIG - If contact was deemed significant

VZV leads to fetal varicella syndrome in babies (skin scarring, eye defects, limb hypoplasia, microcephalic)

Question 4

VZV immunity testing in pregnant mother comes back as negative (she is not immune)

What treatment do you give?

Answer 4

Advise to stay clear of chicken pox and if significant contact is made to come to ED for VZIG

should have VZV immunisation post partum

Question 5

Neonatal hydrocephalus:

Rubella,
CMV
or
Toxoplasmosis

Answer 5

Toxoplasmosis
- Cerebral calcification, Hydrocephalus, Chorioretinitis

ALSO:
-anaemia, hepatosplenomegaly, cerebral palsy

Question 6

Neonatal purpuric skin lesions:

Rubella,
CMV,
or Toxplasmosis

Answer 6

CMV (Rubella can cause too but less frequently)

ALSO:
sensorineural deafness, encephalitis, pneumonitis, hepatosplenomegaly, anaemia, jaundice, cerebral palsy

Question 7

What is the most likely cause of cyanotic congenital heart disease at birth?

at 1-2 months?

Answer 7

birth: Transposition of great arteries

1-2 months: Tetralogy of fallot (overiding aorta, VSD, pulmonary stenosis. right ventricular hypertrophy)