Infection

Question 1

Organism Responsible for cellulitis

Answer 1

Strep Pyogenes

also staph. aureus (less common)

Question 2

Classification system for cellulitis

Answer 2

ERON classification

Question 3

Eron 1 Treatment

Answer 3

Flucoxacillin

Penicillin allergic –> Clarithromycin
Penicillin allergic pregnancy –> erythromycin

Question 4

Eron 3+4 Treatment

Answer 4

1. Admit to hospital
2. oral / IV co-amoxiclav
   or clindamycin
   or IV Cefuroxime
   or IV Ceftriaxone

Question 5

5 main targets for antibiotics

Answer 5

1. Inhibition of cell wall synthesis
2. inhibition of protein synthesis
3. inhibition of nucleic acid synthesis
4. Disrupting cell membrane function
5. Inhibition of metabolites

Question 6

Antibiotics that inhibit cell wall synthesis

Answer 6

1. penicillins
2. cephalosporins
3. glycopetides (vancomycin)

Question 7

Antibiotics that inhibit protein synthesis

Answer 7

30S Subunit:
- aminoglycosides (gentamicin)
- tetracyclines

50S subunit:
- macrolides (erythromycin)
- clindamycin

Question 8

Antibiotics that inhibit nucleic acid synthesis

Answer 8

Quinolines (ciprofloxacin)

Question 9

Antibiotics that inhibit metabolites

Answer 9

Sulfanamides

Question 10

Antibiotics that disrupt the cell membrane

Answer 10

Polymyxin B

Question 11

Prophylaxis for contact with Meningitis patient

Answer 11

1. Single dose of CIPROFLOXACIN / rifampicin
2. Meningocococcal vaccination