Infecções Flashcards
Infecção fúngica - Quais os padrões morfológicos dos patógenos?
Levedura
Hifa
Dimórfico
Infecção leveduras - Principais patógenos?
Cryptococcus neoformans
Candida albicans
Cryptococcus neoformans - Where the organism can be found?
Bird feces (pigeo droppings)
Cryptococcus neoformans - Where does the infection start?
In the lungs through inhaled spores
Cryptococcus neoformans - How is the diagnosis made?
India ink stain
Cryptococcus neoformans - How does the yeast enter the CNS?
Through hematogenous dissemination
Cryptococcus neoformans - Patterns of lesion
Leptomeningeal enhancement (may be nodular) Cryptococcomas Pseudocysts in the basal ganglia
Cryptococcus neoformans - Cryptococcoma size
Miliary (< 3 mm) or Larger
Cryptococcus neoformans - Pseudocyst occupy which space?
Perivascular spaces with gelatinous material
Candida albicans - Common in which population?
Patient receiving immunosuppressive therapy or with indwelling catheters
Candida albicans - Which characteristics make the fungus more invasive?
The ability to shift from yeast to pseudohyphal form
Candida albicans - Pattern
Microabscesses (< 3 mm)
Angioinvasion with thrombosis and hemorrhage
Candida albicans - Uncommon patterns
Meningitis
Macroabscesses
Molds - Pathogens
Aspergillus
Mucorales
Molds - Patterns of invasion
More likely to invade the parenchyma