Infants, Toddlers, Adolescents, Elderly Flashcards
Preemie baby fat needs
Need lots of fat
If cannot digest it need predigested or MCT
Need essential fatty acids - linoleic, alpha-linolenic, EPA and DHA
DHA makes a huge difference in IQ
Corrected gestational age
Recognizing that a preterm baby will not behave and grow like a term baby - give them a corrected age like -3 months when they are born 3 m premature. Used in hospitals
Benefits of breastmilk to preemie babies
Do far better with intelligence
Less problems
Much less necrotizing enterocolitis
Disorganized feeding
If it hurts babies to feed they won’t want to eat. Grow up believing eating is painful and have trouble maintaining their body weight
Oral hypersensitivity
Type of disorganized feeding where the baby misses a critical feeding window (ie, learning how to chew) that they don’t want the good in their mouth.
Inborn errors of metabolism
PKU Maple Syrup Urine Disease Galactosemia Down Syndrome Autism
How many tests done in CO for inborn errors of metabolism
38
Why might newborn screening tests have to be done twice?
Baby has to have drank milk for 24 hours in order for tests to work but tested and discharged too soon.
Autosomal recessive trait
Both parents need to have the recessive gene, and there is a 25% chance of the baby getting the disease
PKU caused by
Lack of phenylalanine hydroxylase, the enzyme that converts excess phenylalanine (an essential AA) into tyrosine so the phenylalanine doesn’t build up and cause brain damage
PKU diet
Diet customized for patient that does not have excess phenylalanine in it. Need some Phe because it is an essential AA - balance to find the right amount
Lofenalac
Formula for PKU patients where most of the Phe is taken out and it is fortified with Tyr.
Phenyl Free
Formula for PKU patients. Tastes vile.
How long do patients with PKU need to be on PKU diet?
Forever. Used to be able to go off diet when a teenager, but have found that you lose IQ points
What happens when woman with PKU gets pregnant
Unlikely that baby gets PKU. But baby is en utero the baby has PKU and the mom has to go back on the formula/diet because the effects on development are severe.
Food with high phenylalanine
Milk
Meat
Diet soda
Preemie babies kcal and protein needs
120 kcal/kg or higher if infections
3 - 3.5 g protein/kg
Branched chain AAs
Isoleucine
Leucine
Valine
Are in high concentration in muscles
Maple syrup urine disease
- Cannot break down branched chain AAs.
- Baby will convulse and die if not treated
- baby esp urine smell like maple syrup
Treatment for maple syrup urine disease
- Protein free diet and formula with no BCAA. Have to make sure they have enough of the AAs but not any extra.
- sometimes put on dialysis
- kids can be doing well until they get sick, and then their levels skyrocket
Galactosemia
Lack the enzyme to break down galactose (component of lactose) which is in breastmilk and formula
Treatment for galactosemia
Use soy formula or lactose free formula - read label.
No cheese even though 99% lactose free
No green beans, organ meat, legumes - have lactose
Effects of galactosemia
Mental impairment and females have trouble reproducing
Down syndrome - another name
Trisomy 21